isotretinoin

(redirected from Amnesteem)
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Related to Amnesteem: isotretinoin, Claravis, Sotret

isotretinoin

 [i″so-tret´ĭ-no-in]
a synthetic form of retinoic acid (13-cis-retinoic acid), used orally to clear cystic and conglobate acne.

i·so·tret·i·noin

(ī'sō-tret'i-noyn),
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

/iso·tret·i·noin/ (i″so-tret´in-o-in) a synthetic form of retinoic acid, used orally to clear cystic and conglobate acne.

isotretinoin

(ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

isotretinoin

[-trətin′ō·in]
an antiacne agent.
indication Subject to significant restrictions, it is prescribed for the treatment of severe cystic acne.
contraindications Pregnancy or sensitivity to the medication or any of its components prohibits its use.
adverse effects A powerful teratogen, young females must be thoroughly educated about the risk of pregnancy and are often placed on birth control pills. The most serious adverse effects to users are epistaxis, cheilitis, conjunctivitis, paresthesia, dizziness, and serum lipid and hematologic disturbances. It may also lower bone mineral density, a consideration for those participating in sports. Some patients become severely depressed or psychotic, which can make them aggressive or suicidal.

isotretinoin

Retinoic acid, 13-cis retinoic acid A retinoid used to treat acne and psoriasis and may ↓ tumor development Side effects Inflammation of skin and mucosa, hepatitis

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

A RETINOID drug used to treat ACNE. The oral preparation is used under strictly controlled conditions to exclude pregnancy because of the known risks to the fetus. Brand names are Roaccutane, and, for external use Isotrex and Isotrexin.

Isotretinoin

A powerful vitamin A derivative used in the treatment of acne. It can promote scarring after skin resurfacing procedures.
Mentioned in: Acne, Skin Resurfacing

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; known human teratogen.

isotretinoin

(ī´sōtret´inoin),
n brand name: Accutane;
drug class: retinoic acid isomer, vitamin A derivative;
action: decreases sebum secretion, improves cystic acne;
uses: severe recalcitrant cystic acne.

isotretinoin

a synthetic form of retinoic acid (13-cis-retinoic acid), used in dermatology for the treatment of disorders of keratinization. It is a potent teratogen.
References in periodicals archive ?
Amnesteem will be available in 10-mg, 20mg, and 40-mg soft-gelatin capsules, as is Accutane, and will be sold in packages of 30 and 100 capsules.
Approximately 77% of the increase in Brand Segment net revenues resulted from sales of Amnesteem, a product launched in late fiscal 2003, with the remainder attributable to growth in the Company's existing portfolio of products.
9 million also as a result of pricing pressures due to additional competition, with Amnesteem and Digitek the two products most affected.
The company further stated that this FDA notification does not impact the commercial status of Amnesteem.
8 million was primarily driven by increased competition on certain branded products, such as Amnesteem, Digitek(R) and Acticin(R), partially offset by higher revenues from phenytoin.
Amnesteem was launched late in the third quarter of fiscal 2003, and contributed net revenues of $61.
on behalf of Genpharm as Amnesteem, Ranbaxy as Sotret and Roche as Accutane.
We are excited about the introduction of Amnesteem by Bertek Pharmaceuticals and its financial performance.
This increase is primarily the result of favorable product mix, with phenytoin comprising a higher percentage of sales, and Amnesteem, which contributes lower gross margins as a result of royalties paid under a supply and distribution agreement, comprising a smaller percentage.
Amnesteem is bioequivalent and thus therapeutically equivalent to Roche Laboratories' Accutane(R) capsules.
The increase was a result of a favorable product mix, primarily a lower concentration of sales from Amnesteem, which contributed lower gross margins as a result of royalties paid under a supply and distribution agreement.