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ammonium |
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ammonium /am·mo·ni·um/ (ah-mo´ne-um) the hypothetical radical, NH4, forming salts analogous to those of the alkaline metals. ammonium carbonate a mixture of ammonium bicarbonate (NH4HCO3) and ammonium carbamate (NH2CO2NH4), used as a stimulant, as in smelling salts, and as an expectorant. ammonium chloride a systemic and urinary acidifying agent and diuretic, also used orally as an expectorant. ammonium lactate lactic acid neutralized with ammonium hydroxide, applied topically in the treatment of ichthyosis vulgaris and xerosis.
ammonium a hypothetical radical, NH4, forming salts analogous to those of the alkaline metals. See also ammonia. ammonium acetate a weak diuretic and feed supplement. ammonium bifluoride wood preservative; causes diarrhea and fall in milk yield in cattle. ammonium carbonate, ammonium chloride saline expectorants used for the purpose of liquefying pulmonary secretions. Effectiveness has not been proven. They are sometimes used as a reflex stimulant because of the strong ammonia given off. The chloride salt is used mainly as a urinary acidifier. Excessive dosage may produce acidosis. ammonium magnesium phosphate see magnesium ammonium phosphate. ammonium metavanadate experimentally causes vanadium poisoning. ammonium nitrate causes nitrate poisoning. ammonium oxalate causes oxalate poisoning. ammonium phosphate a feed additive for cattle. The monobasic salt provides 27% phosphorus and 13% nitrogen, while the dibasic salt provides 23% phosphorus and 21% nitrogen. ammonium sulfamate used as a herbicide; cattle and deer eating treated plants may be poisoned. ammonium sulfate causes ammonia poisoning. storage lesion Transfusion medicine The constellation of changes occurring in a unit of packed red cells during storage. See Red cell preservatives.
Storage lesions
↑ Ammonium to 470 µmol/L–US: 800 µg/dL
↑ Free Hb in plasma from 82 to 6580 mg/L–US: 8.2 to 658 mg/dL
↑ K+ from 4.2 to 78.5 mmol/L–US: 4.2 to 78.5 mEq/L
↓ ATP from 100% to 45%
↓ 2,3 DPG to < 10% of original levels–replenished within 24 hours of transfusion
↓ Labile proteins, eg complement, fibronectin and coagulation factors ↓ to negligible
↓ Na+ from 169 to 111 mmol/L–US: 169 to 111 mEq/L
↓ pH from 7.6 to 6.7
Adverse physiologic effects of stored blood is negligible in the absence of a previous compromise of the Pt's–recipient's status
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