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amitriptyline

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amitriptyline /am·i·trip·ty·line/ (am″ĭ-trip´tĭ-lēn) a tricyclic antidepressant with sedative effects; also used in treating enuresis, chronic pain, peptic ulcer, and bulimia nervosa.
am·i·trip·tyl·ine (m-trpt-ln)
n.
A tricyclic antidepressant drug.

amitriptyline
[am′itrip′tilin]
a tricyclic antidepressant.
indication It is prescribed in the treatment of depression and has unlabeled uses for treating neuropathic pain and headaches.
contraindications Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, or known hypersensitivity to this drug or to other tricyclic medications prohibits its use. It is used with caution in patients who have a seizure disorder or cardiovascular disease or who are at risk for suicide.
adverse effects Among the more common adverse reactions are sedation and anticholinergic effects. A variety of cardiovascular and central nervous system effects may occur. This agent interacts with many other drugs.

amitriptyline
a tricyclic antidepressant in humans; used in dogs and cats to treat psychodermatosis and as an antipruritic.

amitriptyline
Elavil Neuropharmacology A tricyclic antidepressant, with sedative and anticholinergic properties, which may be used for peripheral neuropathy Adverse effects Rash, nausea, weight gain/loss, drowsiness, nervousness, insomnia, confusion, seizures, coma, orthostatic hypotension


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These include the anti-epileptic drugs topiramate (Topamax) and sodium valproate (Depakote), tricyclic antidepressants such as amitriptyline (Elavil) and nortriptyline (Pamelor), beta blockers such as propranolol (Inderal), calcium blockers such as verapamil, and the antihistamine cyproheptadine (Periactin) in children.
These risks were similar among people treated with an SSRI--either fluoxetine (Prozac) or paroxetine (Paxil)--or a tricyclic antidepressant-either amitriptyline or dothiepin.
Some success was reported with the tricyclic antidepressants amitriptyline (4) and nortriptyline, (5,6) but Mihail et al (7) found that trimipramine was not superior to placebo.
 
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