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aminoquinoline

   Also found in: Acronyms, Wikipedia 0.01 sec.
aminoquinoline /ami·no·quin·o·line/ (ah-me″no-kwin´o-lēn) a heterocyclic compound derived from quinoline by the addition of an amino group; the 4-aminoquinoline and 8-aminoquinoline derivatives constitute classes of antimalarials.
aminoquinoline [ah-me″no-kwin´o-lēn]
a heterocyclic compound derived from quinoline by the addition of an amino group; the 4-aminoquinoline and 8-aminoquinoline derivatives are groups of antimalarial agents.


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Studies of complex formation between the bromophenol blue and some important aminoquinoline antimalarials.
Notable examples include nerve damage among individuals homozygous for some variants of the N-acetyltransferase 2 gene ("slow acetylators") given isoniazid as an antituberculosis therapy, hemolytic anemia among glucose 6-phosphate dehydrogenase-deficient patients given aminoquinoline antimalarial drugs, and varied rates of biotransformation of debrisoquine, an antihypertensive drug, due to genetic variation at the CYP2D6 locus (Weber 1997).
APT's patented technology is based on targeted administration of aminoquinolines to inflamed tissues.
 
 
 
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