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aminolevulinic acid |
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aminolevulinic acid /ami·no·lev·u·lin·ic ac·id/ (ALA) (-lev″u-lin´ik) δ-aminolevulinic acid; an intermediate in the synthesis of heme; blood and urinary levels are increased in lead poisoning, and urinary levels are increased in some porphyrias. The hydrochloride salt is used as a topical photosensitizer in the treatment of nonhyperkeratotic actinic keratoses. aminolevulinic acid aminolevulinic acid Oncology A drug used in photodynamic therapy which is absorbed by tumor cells and activated when exposed to light, killing the cells. See Photodynamic therapy. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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DUSA's patents cover the use of
compounds such as aminolevulinic acid (ALA) with PDT to treat actinic
keratosis, basal cell carcinoma, acne and other dermatological
conditions. (R) (NASDAQ NMS:DUSA) announced today it
has filed lawsuits against physicians in California, Florida, and
Tennessee to prevent their continued use of versions of its Levulan(R)
brand of aminolevulinic acid HCl (ALA) produced by compounding
pharmacies, for use in the company's patented photodynamic therapy
(PDT) treatment for actinic keratosis, basal cell carcinoma, acne and
other dermatological conditions. The ALAD gene codes for the enzyme [delta]-aminolevulinic acid
dehydratase (ALAD), which catalyzes the second step of heme synthesis
involving the condensation of two molecules of aminolevulinic acid (ALA)
to form porphobilinogen. |
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