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aminoglutethimide |
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aminoglutethimide /ami·no·glu·teth·i·mide/ (-gloo-teth´ĕ-mīd) an inhibitor of cholesterol metabolism, thereby reducing adrenocortical steroid synthesis; used in the treatment of Cushing's syndrome. It also inhibits estrogen production from androgens in peripheral tissue. aminoglutethimide ( n brand name: Cytadren; drug class: antineoplastic, adrenal steroid inhibitor; action: acts by inhibiting the enzymatic conversion of cholesterol to pregnenolone, thereby blocking synthesis of all adrenal steroids; uses: suppression of adrenal function in Cushing's syndrome, metastatic breast cancer, and adrenal cancer. aminoglutethimide a compound that inhibits the adrenal cortex and peripheral aromatase, thereby blocking production of adrenal steroids. Used in the treatment of hyperadrenocorticism. aminoglutethimide Oncology A nonsteroidal aromatase inhibitor which inhibits estrogen production and suppresses estrogen-dependent tumor growth. See Estrogen-receptor. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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