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amikacin

   Also found in: Wikipedia 0.01 sec.
amikacin /am·i·ka·cin/ (am″ĭ-ka´sin) a semisynthetic aminoglycoside antibiotic derived from kanamycin, used as the sulfate salt in the treatment of a wide range of infections due to aerobic gram-negative bacilli.
amikacin [am″ĭ-ka´sin]
a semisynthetic aminoglycoside antibiotic derived from kanamycin, used as the sulfate salt in the treatment of a wide range of infections due to susceptible gram-negative organisms.

amikacin
Therapeutics The broadest of the broad-spectrum aminoglycosides, which is resistant to aminoglycoside-inactivating enzymes Indications Nosocomial gram-negative bacterial infections–eg, with Enterobacter spp, Klebsiella spp, Proteus spp, Pseudomonas aeruginosa, Serratia spp, E coli, possibly MAC Adverse effects Ototoxicity, nephrotox-icity


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Some of such drugs under this group are Tobramycin, Kanamycin, Gantamycin, Amikacin, Streptomycin, Neomycin and Netilmycin.
Unfortunately, notably high-level resistance to colistin and amikacin was found in the isolate we have described (Table).
The patient underwent excision of the sinus tract, debridement, and L3 corpectomy with anterior spinal fusion, using a combined anterior and posterior approach, followed by intravenous injections of amikacin 750 mg twice per week for 2 months and oral ethambutol 800 mg daily and rifampicin 600 mg daily for one year.
 
 
 
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