Ligands for the oxovanadium(IV) cation: Design, Synthesis, Structure, Spectroscopic and Electrochemical Properties, Inorg.
injection, which is indicated for the induction of general anesthesia.
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Her research focuses on the application of early transition metal amidate
complexes as tunable and novel complexes for the catalytic synthesis of amines.
Polyisocyanates can be stabilized by capping a living polymer chain amidate
anion with an acyl chloride in the presence of an amine catalyst.
Furthermore, recent experimental and theoretical works described that the electrical properties of such composites are dependent on the concentration, type, and aspect ratio of CNTs [18, 19], as well as their state of dispersion and orientation in the matrix , Therefore, properly dispersing and orienting CNTs into polymer substrates has attracted lots of interests, and noncovalent connection of physical adsorption, wrapping, and covalent connection of chemical modification like oxidize and amidate
, even additional magnetic and electric fields were employed to align CNTs individually in the matrix [21-24].
Acknowledging the general activity of Group 4 cyclopentadienyl-based catalysts, Schafer's chelating amidate
ligand offers variable steric and electronic substituents in the backbone, ultimately enabling her to tune the environment about the metal centre for optimal catalysis.
The reason is that all attempts to amidate
PET in the melt resulted so far in crosslinked products.
Food & Drug Administration (FDA) for our novel HIV protease inhibitor GS 9005 and continuing the clinical development of GS 7340, a novel amidate
prodrug of tenofovir, based on favorable Phase I/II results.
We continue to focus resources on the development of other promising candidates in our pipeline, including the co-formulation of Viread(R) (tenofovir disoproxil fumarate) and Emtriva(TM) (emtricitabine) into a single fixed-dose combination tablet, and two investigational agents, GS 7340, an amidate
prodrug of tenofovir, and GS 9005, a protease inhibitor.
Also during the quarter we submitted marketing applications for adefovir dipivoxil for chronic hepatitis B in both the United States and European Union, and initiated Phase I studies of GS 7340, a novel amidate
prodrug of tenofovir for the potential treatment of HIV.