aluminium phosphide


Also found in: Wikipedia.

aluminium phosphide

A pesticide used to fumigate stored grains and rodenticide. Poisoning is more common in farming communities; it is a popular and effective agent for committing suicide in India and Iran. When ingested, it reacts with gastric HCl releasing 1 g of phosphine (10 times its lethal dose), causing death in two hours.

Clinical features
Cardiovascular—arrhythmia, myocarditis, myocardial infarction, hypotensive shock, respiratory distress; GI—epigastric pain, pancreatitis, diarrhoea, vomiting; metabolic effects/chemical pathology—metabolic acidosis, hypercalcaemia, hypomagnesaemia, convulsions, liver failure, kidney failure.
 
Pathogenesis
Vascular damage, RBC membrane damage, cytochrome oxidase inhibition with mitochondrial dysfunction, end-organ hypoxia.

Mechanism
Generates phosphine gas (PH3) in contact with water.

Mortality
High.
References in periodicals archive ?
Tenders are invited for Rate Running Contract For Supply Of Aluminium Phosphide Tablets.
In a release issued by media liaison unit of Punjab agriculture department, experts said farmers should put aluminium phosphide tablets in rat holes and plug them.
The police official said a heavy presence aluminium phosphide, better known as sulphas used as pesticide, was detected in sweets, juices, water and other edibles in the house during forensic tests.
Abdul Alghani, 37, not only lost his infant son but the child's two-year-old brother is still fighting for his life after being exposed to aluminium phosphide.
The tablets contain aluminium phosphide - a highly-toxic substance used to kill rodents underground - which is so dangerous protective suits and breathing equipment is needed when handling it.
Ministry of Environment and Water says it is working on finding 'safer alternatives' to aluminium phosphide
Aluminium phosphide (CAS 20859-73-8) Market Research Report presents comprehensive data on aluminium phosphide markets globally and regionally (Europe, Asia, North America etc.
The autopsy had revealed the detection of traces of celphos -- aluminium phosphide -- in his viscera.
The police is said to have found about 18-20 tablets of aluminium phosphide apparently placed by the tenant on Thursday.
Nine people were taken to hospital while another nine were treated at the dock after being exposed to aluminium phosphide fumes.
Chemicals such as aluminium phosphide and other pesticides are being issued by unlicensed sellers, and improper use can cause serious problems, warn officials.
Police said the vehicle had on board a silver-coloured canister containing the toxic chemical aluminium phosphide.