Alu sequences

Alu se·quenc·es

in the human genome a repeated, relatively conserved sequence of about 300 bp that often contains a cleavage site for the restriction enzyme AluI near the center; about 1 million copies in the human genome.

Alu sequences

a family of repeated DNA sequences found in large numbers in the human genome.
References in periodicals archive ?
Together, the LINE and ALU sequences comprise approximately 30% of the genome (Miki 1998).
In view of the complexity of the premature stop codon mutations in NF1 , the existence of 7 pseudogenes and pseudogene sequences on different chromosomes, and the fact that this gene consists of 58 exons and harbors complex genomic structures, such as repetitive sequences and Alu sequences, NF1 is an ideal clinical target for evaluating the effectiveness of the SCE-NGS method for clinical applications (24,26-29).
Alu sequences are short stretches of DNA with the unusual ability to copy themselves and jump from one chromosome to another.
PCR primers were designed toward consensus LINE-1 and Alu sequences and allowed for the amplification of a representative pool of repetitive elements to serve as a surrogate for diffuse genomic DNA methylation changes.
The breakpoints involved alu sequences, because it has been reported for other BRCA1 deletions (19).
Tens of thousands of Alu sequences lace the human genome, but their functions remain unknown.
ALU sequences are short interspersed elements, typically 300 nucleotides in length, that account for more than 10% of the human genome (12).
Human Cytochrome P450 4 mRNA and gene: part of a multigene family that contains Alu Sequences in its mRNA.
Alu sequences are short interspersed elements that are distributed widely throughout the human genome (10).
Because cell lysate contained mRNA that had Alu sequences, the emission in rlu of the Alu sequence in cell lysate might be higher than that in purified genomic DNA.
We have numbered the nucleotides according to the consensus numbering system for Alu sequences (22).