Alternative-complement-pathway C3/C5 convertase

pathway /path·way/ (path´wa)

1. a course usually followed.

2. the nerve structures through which an impulse passes between groups of nerve cells or between the central nervous system and an organ or muscle.

3. metabolic p..

accessory conducting pathway myocardial fibers that propagate the atrial contraction impulse to the ventricles but are not a part of the normal atrioventricular conducting system.

afferent pathway the nerve structures through which an impulse, especially a sensory impression, is conducted to the cerebral cortex.

alternative complement pathway a pathway of complement activation initiated by a variety of factors other than those initiating the classical pathway, including IgA immune complexes, bacterial endotoxins, microbial polysaccharides, and cell walls. It does not include factors C1, C2, and C4 of the classical complement pathway but does include factors B and D and properdin.

amphibolic pathway a group of metabolic reactions providing small metabolites for further metabolism to end products or for use as precursors in synthetic, anabolic reactions.

circus pathway a ring or circuit traversed by an abnormal excitatory wavefront, as in reentry.

classical complement pathway a pathway of complement activation, comprising nine components (C1 to C9), initiated by antigen-antibody complexes containing immunoglobulins IgG or IgM.

common pathway of coagulation the steps in the mechanism of coagulation from the activation of factor X through the conversion of fibrinogen to fibrin.

Coagulation pathway overview.

efferent pathway the nerve structures through which an impulse passes away from the brain, especially for the innervation of muscles, effector organs, or glands.

Embden-Meyerhof pathway the series of enzymatic reactions in the anaerobic conversion of glucose to lactic acid, resulting in energy in the form of adenosine triphosphate (ATP).

Embden-Meyerhof pathway of glucose metabolism.

extrinsic pathway of coagulation the mechanism that produces fibrin following tissue injury, beginning with formation of an activated complex between tissue factor and factor VII and leading to activation of factor X, inducing the reactions of the common pathway of coagulation.

final common pathway a motor pathway consisting of the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.

intrinsic pathway of coagulation a sequence of reactions leading to fibrin formation, beginning with the contact activation of factor XII, and resulting in the activation of factor X to initiate the common pathway of coagulation.

lipoxygenase pathway a pathway for the formation of leukotrienes and hydroxyeicosatetraenoic acid from arachidonic acid.

Lipoxygenase pathway of leukotriene and hydroxyeicosatetraenoic acid synthesis. HPETE, hydroperoxyeicosatetraenoic acid; HETE, hydroxyeicosatetraenoic acid; LT, leukotriene.

metabolic pathway a series of enzymatic reactions that converts one biological material to another.

motor pathway an efferent pathway conducting impulses from the central nervous system to a muscle.

pentose phosphate pathway a major branching of the Embden-Meyerhof pathway of carbohydrate metabolism, successively oxidizing hexoses to form pentose phosphates.

reentrant pathway that over which the impulse is conducted in reentry.

pathway [path´wa]

a course usually followed. In neurology, the nerve structures through which a sensory impression is conducted to the cerebral cortex (afferent pathway), or through which an impulse passes from the brain to the skeletal musculature (efferent pathway). Also used alone to indicate a sequence of reactions that convert one biological material to another (metabolic pathway).

accessory pathway (accessory conduction pathway) extra muscle tissue between the atrium and ventricle that bypasses all or part of the normal conduction system. When the ventricles are activated prematurely via this pathway, initial forces are slow, producing the delta wave of wolff-parkinson-white syndrome, and preexcitation is said to exist; the delta wave causes the PR interval to shorten and the QRS interval to broaden.

alternative complement pathway see complement.

amphibolic pathway a group of metabolic reactions with a dual function, providing small metabolites for further catabolism to end products or for use as precursors in synthetic, anabolic reactions. The tricarboxylic acid cycle is an example. See also anabolism and catabolism.

biosynthetic pathway the sequence of enzymatic steps in the synthesis of a specific end-product in a living organism.

classical complement pathway see complement.

coagulation p's see common p. of coagulation, extrinsic p. of coagulation, and intrinsic p. of coagulation.

common pathway of coagulation the steps in the mechanism of coagulation (see clotting) from the activation of factor x through the conversion of fibrinogen to fibrin. See also intrinsic pathway of coagulation and extrinsic pathway of coagulation.

concealed accessory pathway an accessory pathway that has only retrograde conduction; thus its PR and QRS complexes are normal on the electrocardiogram, but there is a tendency to develop premature supraventricular tachycardia. If atrial fibrillation develops, conduction will proceed across the atrioventricular node.

Embden-Meyerhof pathway the series of enzymatic reactions in the anaerobic conversion of glucose to lactic acid, resulting in energy in the form of adenosine triphosphate (ATP).

extrinsic pathway of coagulation the mechanism that produces fibrin following tissue injury, beginning with formation of an activated complex between tissue factor and factor vii and leading to activation of factor x, which induces the reactions of the common pathway of coagulation. See also intrinsic pathway of coagulation.

final common pathway

1. the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.

2. any mechanism by which several independent effects exert a common influence.

intrinsic pathway of coagulation a sequence of reactions leading to fibrin formation, beginning with the contact activation of factor xii. This is followed by the sequential activation of factors xi and ix, which results in the activation of factor x. Activated factor X (factor Xa) initiates the common pathway of coagulation. See also extrinsic pathway of coagulation.

pentose phosphate pathway a pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final forming a pentose phosphate.

alternative complement pathway

Properdin pathway Immunology A route of complement activation that occurs independently of complement-fixing antibodies; the ACP is more complex than the classic complement pathway; it requires a 'priming' C3 convertase–C3,Bb, and an 'amplification' C3 convertase–C3b,Bb; in the presence of properdin, C3 convertase is stabilized, activating later complement components, which leads to opsonization, leukocyte chemotaxis, ↑ vascular permeability, and cytolysis; ACP is activated by properdin, IgA, IgG, lipopolysaccharide, and snake venom; both pathways are stimulated by trypsin-like enzymes. Cf Complement.

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accelerator factor angiogenesis factor antihemophilic factor antinuclear factor C3 nephritic factor Christmas factor extrinsic factor factor factor B factor D factor H factor I fibrin-stabilizing factor Fitzgerald factor Fletcher factor granulocyte colony-stimulating factor granulocyte-macrophage colony-stimulating factor growth factor Hageman factor			alternating current alternating hemiplegia alternating hypertropia alternating mydriasis alternating pulse alternating tremor alternation alternation of generations alternation of heart alternation rules alternative alternative benefit plan alternative birthing center alternative complement pathway alternative delivery system alternative healing alternative hypothesis alternative inheritance alternative lifestyle alternative medicine alternative pathway of complement activation alternative site provider alternative states of consciousness Alternative therapy alternative treatment plan Alternative-complement-pathway C3/C5 convertase alternator alternobaric alternobaric trauma alternobaric vertigo ALTEs Althaea officinalis althesin altitude Altitude Anoxia altitude decompression sickness altitude disease altitude sickness altitudinal hemianopsia Altocor altrenogest altretamine altricial Altromed-S altruism Altruistic Suicide Alu family Alu sequences alula alula spuria alum			alternative treatment plan Alternative Treatment Technology Information Center Alternative Urban Areawide Review Alternative Valuation Date Alternative Valuation Dates Alternative Vehicles Task Force Alternative Ventures for at Risk Youth Alternative Veterinary Medicine Centre Alternative views on the origin of mankind Alternative Vision of Business Alternative vote Alternative vote Alternative Water Supply Alternative Ways of Filing Alternative Whisky Academy Alternative Work Arrangement Alternative Work Environment Alternative Work Experience Program Alternative Work Force Alternative Work Schedule Alternative Workplace Arrangements Alternative Workplace Strategies alternative workspace Alternative Writ Alternative Youth Centre for Employment Alternative-complement-pathway C3/C5 convertase Alternative-Fuel Motor Vehicle Alternative-Fuel Vehicle Alternative-South Texas Educator Program Alternative2punk alternatively alternatively alternatively alternatively activated macrophage Alternatively Refined Carrageenan Alternativen für Gutes Licht Alternativen zu Tierexperimenten Alternativeness Alternatives Alternatives Alternatives Alternatives Analysis Integrated Project Team Alternatives for Community and Environment Alternatives for Girls Alternatives for Independent Youth Alternatives for Youth Alternatives in Education for the Hearing Impaired Alternatives in Publication Alternatives Jugendzentrum Alternatives Médecines Evolutives Santé et Sciences Innovantes Alternatives of Benefits and Cost Alternatives to Abortion International Alternatives to Animal Testing and Experimentation Alternatives to Animal Use Committee

alternative complement pathway (redirected from Alternative-complement-pathway C3/C5 convertase)

alternative complement pathway
(redirected from Alternative-complement-pathway C3/C5 convertase)