Alström's syndrome

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Alström's syndrome

Etymology: Carl Henry Alström, Swedish geneticist, 1907-1993

an inherited disease characterized by multiple system resistance to hormones. Clinical features include retinal degeneration leading to childhood blindness, type 2 diabetes mellitus, infantile obesity, nerve deafness, baldness, hyperuricemia, and hypertriglyceridemia. Males may also have high plasma gonadotropin levels and hypogonadism. The condition is transmitted through an autosomal-recessive gene.

Alström's syndrome [al´stromz]

an autosomal recessive syndrome usually occuring after age 10, consisting of retinitis pigmentosa with nystagmus and early loss of central vision, deafness, obesity, and diabetes mellitus.

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