Alphavirus /Al·pha·vi·rus/ (al´fah-vi″rus) a genus of viruses of the family Togaviridae that cause encephalitis or febrile illness with rash or arthralgia.
alphavirus
alphavirus
| Alphavirus n. A genus of viruses of the Togaviridae family. |
al·pha·vi·rus ( l f -v  rs)n. A member of the genus Alphavirus. |
alphavirus
[al′favī′rəs]
any of a group of very small togaviruses consisting of a single molecule of single-stranded ribonucleic acid within a lipoprotein capsule. Many alphaviruses multiply in the cytoplasm of cells of arthropods and are transmitted to humans from mosquitoes, such as those causing equine encephalitis and Semiliki Forest virus. See also encephalitis, togavirus.
Alphavirus
one of the two genera in the family Togaviridae; includes eastern, western and Venezuelan equine encephalomyelitis viruses and Getah virus. All of them replicate in arthropod vectors including mosquitoes.
alphavirus
Group A arbovirus Virology A genus of the family Togaviridae characterized by 50-60 nm virions containing a single-stranded linear RNA Pathogenic alphaviruses Eastern, western, and Venezuela equine encephalitis viruses, Sindbis
virus and Semliki Forest viruses–which may be used as vectors for expressing heterologous genes, Ross River, o'nyong-nyong virus Epidemiology Pathogenic alphaviruses of the Western hemisphere occur primarily in the summer Clinical
Headache, fever, chills, N&V, mental confusion, somnolence Laboratory Lymphocytosis and ↑ protein in CSF Management Supportive, intensive nursing care Sequelae Neurologic effects–eg, mental retardation, convulsions, paralysis in
30–70% of survivors
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