cyclodextrin

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cyclodextrin

(sī-klō-dĕks′trĭn)
A molecule made of linked dextrose subunits that can be used in drug delivery in the body. Cyclodextrins have lipid centers surrounded by water-soluble exteriors. This combination allows fat-soluble medicines to be carried through the bloodstream to lipid-rich organs like the brain.
References in periodicals archive ?
Due to the molecular structure of saturated fats, these pro-inflammatory fats are strongly attracted to the soluble alpha-cyclodextrins.
Researchers have identified a natural fiber called alpha-cyclodextrin that selectively absorbs and eliminates bad fats such as trans fat or saturated fat while leaving good fats like omega-3s untouched to deliver their benefits.
Studies showed that if alpha-cyclodextrin were taken three times a day during high-fat meals (2 grams per meal), one could engulf as much as 2 ounces of trans fat and saturated fat each day, which represents up to 500 calories of pure fat that never gets absorbed into the bloodstream.
For example, for people who eat two heavy-fat meals a day, (3) 2 grams of alpha-cyclodextrin taken before each of these meals can remove up to 320 calories from the body before absorption.
Alpha-cyclodextrin can be a helpful strategy in maintaining healthy cholesterol and triglyceride levels while reducing the risk of metabolic syndrome.
Human research demonstrates that alpha-cyclodextrin can be a highly useful component in controlling the negative impact of harmful fats before they enter the bloodstream.
Unlike alpha-cyclodextrin, these medications rely on inhibiting the lipase enzyme that breaks down triglycerides (the major form of dietary fat) into single fatty acid molecules.
Alpha-cyclodextrins are annular, purely plant-based molecules which are obtained from renewable raw materials, such as potatoes and corn.
536/2013 on the list of permitted health claims made on foods ascribes a scientifically accepted blood-sugar-regulating effect to alpha-cyclodextrin: Consumption of alpha-cyclodextrin as part of a starch-containing meal contributes to the reduction of the blood sugar rise after that meal.
Food containing at least five grams of alpha-cyclodextrin per 50 grams of starch in a quantified portion as part of a meal may now carry a label claiming the blood-sugar-lowering effect of the product.
The blood-sugar-lowering effect of alpha-cyclodextrin means that it lowers the glycemic index (GI) of foods, a fact which is important not only to diabetics: such products are digested more slowly and so keep the blood sugar level at a consistently low level.
The food industry uses alpha-cyclodextrin as a water-soluble dietary fiber, e.