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alpha-2-macroglobulin

   Also found in: Acronyms, Wikipedia 0.03 sec.
alpha-2-macroglobulin
Alpha-2-M, antiplasmin An 800 kD protein, which maps to chromosome 12 which inhibits proteases–trypsin, chymotrypsin, elastase, thrombin, plasmin Ref range 125–420 mg/dL, higher in ♀ ↑ A2M Liver disease, DM, nephrotic syndrome, neural tube defects, ↑ estrogen, pregnancy, neonates and children, ataxia-telangiectasia ↓ A2M Protein-losing gastroenteropathy, protein malnutrition, DIC, fibrinolytic therapy


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These compounds include LDL ("bad") cholesterol, fibrinogen, alpha-2-macroglobulin and other defined substances believed to be associated risk factors for macular degeneration.
 
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