The primary defect which allows this to occur is the inherited deficiency of the enzyme, alpha galactosidase
A, which is normally responsible for the breakdown of globotriaosylceramide.
x x japonica GN=Osl0g0493600 PE=1 SV=1 Acid alpha galactosidase
1 OS=Cucumis sativus PE=2 x x SV=1 Alpha-xylosidase OS=Arabidopsis lyrata x x GN=ARALYDRAFT_894626 PE=4 SV=1 Peroxidase (Fragment) OS=Lupinus polvphyllus PE=2 x x SV=2 Alpha-xylosidase OS=Arabidopsis thaliana GN=XYLI x x PE=1 SV=1 Beta-galactosidase 1 OS=Oryza sativa subsp.
The Beano enzyme, alpha galactosidase
(come in, starship command), helps break down the oligosaccharides, preventing fermentation, thus averting juvenile tricks with lit matches.
NYSE AMEX: IBIO) today announced the engagement of CBR International Corporation (CBR) for strategic regulatory and clinical services to advance iBio's Orphan Drug designated, plant-produced human alpha galactosidase
A ("-Gal A") enzyme candidate for development as a therapeutic option for patients with Fabry disease.
The disease is caused by a genetic mutation that results in a lack of, or low level or activity of, an enzyme called alpha galactosidase
A (a-Gal A).
NYSE AMEX:IBIO) today announced it has acquired Orphan Drug Designation for plant-produced human alpha galactosidase
A ("-Gal A") and related property rights from an affiliate of Kentucky Bioprocessing LLC ("KBP") and has initiated a program, based on its iBioLaunch[TM] platform, to develop an improved version of the enzyme for therapy of Fabry disease.
Gelderman et al, and published in PreClinica, Jan/Feb 2004, profiles preclinical research on the characteristics of a plant-made alpha galactosidase
in the mouse model for Fabry disease pioneered by Dr.