paracoccidioidomycosis

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paracoccidioidomycosis

 [par″ah-kok-sid″e-oi″do-mi-ko´sis]
an often fatal, chronic granulomatous disease caused by Paracoccidioides brasiliensis; it is endemic in Brazil and also occurs elsewhere in South and Central America and in arid regions of the southwestern United States. Infection primarily involves the lungs, but spreads to the skin, mucous membranes, lymph nodes, and internal organs. Amphotericin B is the specific drug used for treatment. Called also South American blastomycosis.

par·a·coc·cid·i·oi·do·my·co·sis

(par'ă-kok-sid'ē-oy'dō-mī-kō'sis),
A chronic mycosis characterized by primary pulmonary lesions with dissemination to many visceral organs, conspicuous ulcerative granulomas of the buccal and nasal mucosa with extensions to the skin, and generalized lymphangitis; caused by Paracoccidioides brasiliensis.

paracoccidioidomycosis

/para·coc·cid·i·oi·do·my·co·sis/ (-kok-sid″e-oi″do-mi-ko´sis) an often fatal, chronic granulomatous disease caused by Paracoccidioides brasiliensis, primarily involving the lungs, but spreading to the skin, mucous membranes, lymph nodes, and internal organs.

paracoccidioidomycosis

[per′əkoksid′ē·oi′dōmīkō′sis]
Etymology: Gk, para + kokkos, berry, eidos, form, mykes, fungus, osis, condition
a chronic, occasionally fatal fungal infection caused by Paracoccidioides brasiliensis. It is characterized by ulcers of the oral cavity, larynx, and nose. Other effects include large, draining lymph nodes; cough; dyspnea; weight loss; and skin, genital, and intestinal lesions. The disease occurs in Mexico and Central and South America and is acquired by inhalation of spores of the fungus. Diagnosis is by microscopic examination of a smear prepared from a lesion. This infection is sensitive to the use of sulfonamides, amphotericin B, and the azole antifungals. Azoles are preferred over sulfonamides and amphotericin B because they are less toxic, more effective, and require a shorter duration of treatment. Azoles are available in an oral form. Also called paracoccidioidal granuloma, South American blastomycosis. Compare North American blastomycosis.

par·a·coc·cid·i·oi·do·my·co·sis

(par'ă-kok-sid'ē-oy'dō-mī-kō'sis)
A chronic fungal disease characterized by primary pulmonary lesions with dissemination to many visceral organs, conspicuous ulcerative granulomas of the buccal and nasal mucosa with extensions to the skin, and generalized lymphangitis; caused by Paracoccidioides brasiliensis.
Synonym(s): Almeida disease, Lutz-Splendore-Almeida disease, paracoccidioidal granuloma, South American blastomycosis.

Almeida,

Floriano Paulo de, Brazilian physician, 1898–.
Almeida disease - a chronic mycosis caused by Paracoccidioides brasiliensis. Synonym(s): paracoccidioidomycosis
Lutz-Splendore-Almeida disease - see under Lutz

Lutz,

Alfredo, Brazilian physician, 1855-1940.
Lutz-Splendore-Almeida disease - a chronic mycosis caused by Paracoccidioides brasiliensis. Synonym(s): paracoccidioidomycosis

paracoccidioidomycosis

tropical fungal infection common in Central America; may cause painful, nodular, haemorrhagic ulcerated and verrucous foot lesions

par·a·coc·cid·i·oi·do·my·co·sis

(par'ă-kok-sid'ē-oy'dō-mī-kō'sis)
Chronic mycosis characterized by primary pulmonary lesions with dissemination to many visceral organs, conspicuous ulcerative granulomas of buccal and nasal mucosa with extensions to skin, and generalized lymphangitis; caused by Paracoccidioides brasiliensis.

paracoccidioidomycosis

an often fatal, chronic granulomatous disease of humans, dogs, cats and most mammals caused by Paracoccidioides brasiliensis. The disease is endemic in South America, particularly Brazil. Infection primarily involves the lungs, but spreads to the skin, mucous membranes, lymph nodes and internal organs. Called also South American blastomycosis.