alloxan /al·lox·an/ (ah-lok´san) an oxidized product of uric acid that tends to destroy the islet cells of the pancreas, thus producing diabetes (alloxan diabetes).
alloxan
alloxan (
lok´san),
alloxan
[əlok′san]
an oxidation product of uric acid that is found in the human intestine in diarrhea. Alloxan has been used to produce diabetes in experimental animals by destroying the insulin-secreting islet cells of the pancreas.
alloxan (
lok´san),n a substance, mesoxalyl urea, capable of producing experimental diabetes by destroying the islet cells of the pancreas.
alloxan
an oxidized product of uric acid which destroys β cells of the islets of Langerhans in the pancreas. It has been used in experimental studies of diabetes mellitus and in the treatment of insulinomas in dogs.
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