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Related to Allium sativum: Allicin, Cajanus cajan, Zingiber officinale
Alli sativa bulbus(trade name),
Allium sativum(trade name)
ClassificationTherapeutic: lipid lowering agents
Adverse Reactions/Side Effects
Central nervous system
- Irritation of the mouth, esophagus, and stomach
- bad breath
- Contact dermatitis and other allergic reactions (asthma, rash, anaphylaxis [rare])
- Chronic use or excessive dose may lead to ↓ hemoglobin production and lysis of RBCs
- platelet dysfunction
- prolonged bleeding time
- body odor
InteractionsUse of garlic with anticoagulants, antiplatelet agents and thrombolytics may ↑ risk of bleeding.May ↓ the effectiveness of contraceptive drugs and cyclosporine.May ↓ plasma concentrations of saquinavir, nevirapine, delavirdine, and efavirenz.May ↓ isoniazid levels by 65%.Herbs with anticoagulant or antiplatelet properties may increase bleeding risk when combined with garlic, including: angelica, anise, asafoetida, bogbean, boldo, capsicum, celery, chamomile, clove, danshen, dong quai, fenugreek, feverfew, ginger, ginkgo, Panax ginseng, horse chestnut, horseradish, licorice, meadowsweet, prickly ash, onion, papain, passionflower, poplar, quassia, red clover, turmeric, wild carrot, wild lettuce, willow, and others.
- Elicit from patients their usual dietary intake especially in regard to fat consumption.
- Assess patient’s reason for using this herbal remedy and knowledge about hyperlipidemia.
- Ascertain the amount of garlic the patient consumes on a regular basis.
Potential Nursing DiagnosesDeficient knowledge, related to medication regimen (Patient/Family Teaching)
Noncompliance (Patient/Family Teaching)
- Take orally as fresh clove, capsule or tablet.
- Do not exceed recommended dose.
- Instruct patients about the need to follow a healthy diet (low in fat and high in vegetables and fruits) in conjunction with garlic. Other lipid reducing strategies, such as exercise and smoking cessation, should also be employed.
- Inform patients that there are other more effective agents for lipid reduction available.
- Emphasize the need for follow up exams with a healthcare professional to assess effectiveness of the regimen.
- Warn patients about the potential for bleeding and not to take this herbal remedy without notifying their healthcare provider if they are on other medications. Instruct patients undergoing elective surgery to stop using garlic 2 weeks prior to surgery and to notify the surgeon that they are taking garlic in the event of emergent surgery.
- Notify patients that allergies may occur and to discontinue use if symptoms develop.
- Normalization of lipid profile.
- Prevention of cardiac disease.
Chinese medicine Chinese chive, da suan Garlic is used in traditional Chinese medicine as an antimicrobial and general tonic, and for colds, cough, diarrhoea, gastrontestinal complaints, parasites, rheumatic disease, shellfish poisoning, tuberculosis, tumours and vaginitis, as well as to increase internal secretions, and topically for athlete’s foot, fungal and parasitic infections. See Chinese herbal medicine
Herbal medicine In Western herbal medicine, garlic is used internally for atherosclerosis, colds, coughs, flu, gastrointestinal complaints, hypercholesterolemia, hypertension, liver and gallbladder disease and as an anthelmintic; as with Chinese herbal medicine, it is used topically for athlete’s foot, fungal and parasitic infections and as a rubefacient. See Herbal medicine
Allium sativum(al′ē-ŭm să-tē′vŭm, tī′) [L., planted garlic]
Patient discussion about Allium sativum
Q. Is garlic helpful in heart ailments? I have heard that garlic is very good for cardiac health and using in curries or cooked with foods will be helpful. I have also heard that it has anti-inflammatory substances and also helps in weight loss. Is garlic helpful in heart ailments?