allele frequency

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allele frequency

A term used in population genetics for the number of copies of a particular allele divided by the number of copies of all alleles at that specific genetic locus in a population of interest. Allele frequency is a measure of a population’s genetic diversity: the higher the allele frequency, the greater the population’s consanguinity.
Allele frequencyclick for a larger image
Fig. 23 Allele frequency . Calculation of allele frequency from genotype frequency.

allele frequency

or

gene frequency

the proportion of a particular ALLELE of a gene in a population, relative to other alleles of the same gene. For example, if a gene has two alleles, A and a , and the frequency of A is 0.6, then the frequency of a will be 1.0 - 0.6 = 0.4. The allele frequency can be calculated from the GENOTYPE FREQUENCY; See Fig. 23 .
References in periodicals archive ?
The first ctDNA product available for early access is a five mutation mixture at varying allele frequencies from 10% down to 1%.
Furthermore, the purpose of the study was to determine the inter-ethnic variability of allele frequencies of the above genes among the south Indians with the HapMap and other populations from previously published reports.
As shown in Table 1, there was no significant difference between the major depressive disorder and control groups after the analysis of genotype and allele frequencies of the Ser49Gly polymorphism in the ADRB gene (p=0.
To test for recent evidence of gene flow and the role of each site as a source or sink of larvae, first-generation migrants were identified based on allele frequencies with a Bayesian method (Rannala & Mountain 1997) implemented in GENECLASS2 (Piry et al.
They provide the largest and most detailed set of common as well as rare allele frequencies, critical for advancing more efficient diagnostics; a population-wide collection of human knockouts; and new risk factors for Alzheimer's and a range of other diseases.
26) Genotypes and allele frequencies are represented as percentages and the frequencies were calculated by gene counting method.
This software assumes a model in which there are K populations (clusters) that contribute to the genotype of each individual and are characterized by a set of allele frequencies at each marker locus.
Analysis of genetic variation at microsatellite lock We determined sample allele frequencies at all loci following the procedures of MILLER and KAPUSCINSKI (1996).
Similarly, a power analysis completed on the basis of observed allele frequencies in Gulf Menhaden indicated that these markers can be used to detect very small levels of genetic divergence ([F.
All of the above information, except the null allele frequency, is usually available; however, no published estimates of null allele frequencies in South African populations have been made to date.
Note that the allele frequencies of the splice variants rs11573 and rs7252245 were not significantly different from the allele frequencies reported in dbSNP and by Parikh et al.
VDBP genotypes distribution and allele frequencies in TID patients versus healthy control subjects VDBP SNP Control T1D (n= OR (95% P (n=65) 59) No.