Aleutian mink disease


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A chronic fatal parvoviral infection of minks, which causes a polyclonal expansion of B lymphocytes, and affects minks that are homozygous for the Aleutian blue mink gene

Aleutian mink disease

a slowly progressive disease of certain mink (e.g. Aleutian mink which are mutants for a pale colored pelt) caused by persistent parvovirus infection and associated with polyclonal, virus specific hypergammaglobulinemia and immune complex-mediated lesions, especially arteritis and glomerulonephritis. It is manifested by emaciation, reproductive inefficiency and death from renal failure. The characteristic laboratory findings are hypergammaglobulinemia and a massive proliferation and infiltration of plasma cells into the swollen kidneys and into the spleen, liver, lymph nodes and bone marrow.
References in periodicals archive ?
Subcellular localization of Aleutian mink disease parvovirus proteins and DNA during permissive infection of Crandell feline kidney cells.
Mink that tested positive for this new variant were from herds that had mink enteritis virus, hepatic lipidosis, Aleutian mink disease virus, and catarrhal enteritis, all factors that could explain the clinical and pathologic findings of the mink infected with HEV (15).
Aleutian mink disease parvovirus in wild riparian carnivores in Spain.
Role of alveolar type II cells and of surfactant-associated protein C mRNA levels in the pathogenesis of respiratory distress in mink kits infected with Aleutian mink disease parvovirus.