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alendronate |
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alendronate /alen·dro·nate/ (ah-len´dro-nāt) a bisphosphonate calcium-regulating agent used in the form of the sodium salt to inhibit the resorption of bone in the treatment of osteitis deformans, osteoporosis, and hypercalcemia related to malignancy. Alendronate A nonhormonal drug used to treat osteoporosis in postmenopausal women. Mentioned in: Osteoporosis alendronate, a bone-resorption inhibitor. indications This drug is used to treat osteoporosis in postmenopausal women and Paget's disease. contraindication Known hypersensitivity to biphosphonates prohibits the use of this drug. adverse effects Side effects include anemia, hypokalemia, hypomagnesemia, hypophosphatemia, osteonecrosis of the jaw, abdominal pain, anorexia, constipation, nausea, vomiting, bone pain, hypertension, urinary tract infection, and fluid overload. alendronate Fosamax® Endocrinology A biphosphonate used to treat postmenopausal osteoporosis and Paget's disease of bone. See Osteoporosis. Cf Salmon calcitonin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| In addition, patients can also be treated off-label with
bisphosphonates like alendronate (Fosamax) if risk factors indicate that
they have a high fracture risk. Alendronate sodium
(Fosamax) won't protect against breast cancer, but has fewer side
effects. (14) Alendronate use by osteoporotic patients
has been associated with a severe erosive esophagitis. |
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