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aldose reductase

   Also found in: Wikipedia 0.01 sec.
aldose reductase
An enzyme normally present in the eye and elsewhere, which converts excess glucose–as occurs in DM—into sorbitol; excess sorbitol in the eye, nerves, and kidneys can lead to retinopathy, neuropathy, and nephropathy. See Aldose reductase inhibitors.


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The company has confirmed that chalcones have insulin-like activity and aldose reductase inhibitory activity so that they help prevent and cure diabetes.
-- Zenarestat is an aldose reductase inhibitor licensed from Fujisawa for the prevention of diabetic neuropathy.
 
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