Aldolase B


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Aldolase B

Also called fructose 1-phosphate aldolase, this chemical is produced in the liver, kidneys, and brain. It is needed for the breakdown of fructose, a sugar found in fruits, vegetables, honey, and other sweeteners.
References in periodicals archive ?
Aldolase A is expressed exclusively by fetal liver (5), not the adult tissue, and is involved in the glycolytic pathway (to split or synthesize fructose 1,6-diphosphate), whereas the adult liver expresses mainly the aldolase B isoenzyme (involved in the metabolism of exogenous fructose).
It is caused by any of several molecular abnormalities of the human aldolase B gene (3).
Diagnosis was assayed by conventional methods: intravenous fructose tolerance tests or aldolase B activity assays in liver biopsy samples.