Alder-Reilly anomaly


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Related to Alder-Reilly anomaly: gargoylism, Chediak-Higashi anomaly, Auer bodies, May Hegglin Anomaly

Alder-Reilly anomaly

A haematologic finding characterised by large, intensely azurophilic granules in the cytoplasm of neutrophils, lymphocytes, and monocytes, accompanied by defects in eosinophilic and basophilic granules. It is associated with mucopolysaccharidoses and linked to various enzymopathies.

Alder-Reilly anomaly

Genetics An AD condition characterized by large, intensely azurophilic granules in the cytoplasm of PMNs, lymphocytes, and monocytes, accompanied by defects in eosinophilic and basophilic granules

Alder-Reilly anomaly

(al′dĕr-rī′lē)
[Albert von Alder, Swiss hematologist, 1888–1951; William Anthony Reilly, U.S. pediatrician, b. 1901.]
Large dark leukocyte granules that stain lilac. They consist of mucopolysaccharide deposits and are indicative of mucopolysaccharidosis.

Alder,

Albert von, 1888–.
Alder anomaly - coarse azurophilic granulation of leukocytes, especially granulocytes, which may be associated with gargoylism and Morquio disease.
Alder bodies - granular inclusions in polymorphonuclear leukocytes.
Alder-Reilly anomaly - Synonym(s): Reilly bodies

Reilly,

William A., U.S. pediatrician, 1901–.
Reilly bodies - peripheral blood that has basophilic and azurophilic granules in granulocytes that are larger in size than usual. Synonym(s): Alder-Reilly anomaly
Alder-Reilly anomaly - Synonym(s): Reilly bodies