aldehyde reductase

al·co·hol de·hy·dro·gen·ase (NADP+)

(al'kŏ-hol dē-hī-droj'e-nās),
An oxidoreductase that reversibly converts alcohols to aldehydes (or ketones) with NADP+ as hydride acceptor.
Synonym(s): aldehyde reductase

aldehyde reductase

/al·de·hyde re·duc·tase/ (re-duk´tās) an enzyme that catalyzes the reduction of aldoses; in one form of galactosemia, its catalysis of reduction of excess galactose in the lens of the eye results in cataract formation.


A gene on chromosome 4q21-23 that encodes class-I alcohol dehydrogenase, alpha subunit, a member of the alcohol dehydrogenase family, which metabolise various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. The encoded protein plays a major role in ethanol catabolism and is highly expressed in adults livers.
References in periodicals archive ?
Aldehyde dehydrogenases mediate the oxidative pathway of carbonyls, forming carbonic acids [71, 72]; glutathione-S-transferases (GST) catalyze the conjugation of carbonyls with glutathione [73-75]; and aldehyde reductase and aldo-keto reductases (AKRs) are responsible for the reduction of carbonyls to alcohols with NAD(P)H as a coenzyme [75-77].
3]CH=CHCHO) (2) Aldehyde reductase and aldo-keto reductases (AKRs) catalyze reduction to alcoholic forms Malondialdehyde (OCHC[H.
Aldehyde dehydrogenase and aldehyde reductase in isolated bovine brain microvessels.