ALDH9A1

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ALDH9A1

A gene on chromosome 5q31 that encodes an aldehyde dehydrogenase which catalyses the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA).
References in periodicals archive ?
Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells.
Polymorphisms in the mitochrondrial aldehyde dehydrogenase gene (Aldh2) determine peak blood acetaldehyde levels and voluntary ethanol consumption in rats.
Brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: Relations to strain, sex and age.
Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage.
Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an Aldh2 antisense mRNA.
ALDH2 deficiency, sometimes referred to as "Asian flushing syndrome," is an inherited metabolic disorder affecting 40% to 50% of East Asian populations, impairing the activity of the liver enzyme aldehyde dehydrogenase ("ALDH2").
Likewise, having the ALDH2*2 allele, which inactivates aldehyde dehydrogenase, has protective effects on both alcohol intake and esophageal cancer.
A year ago, Ziouzenkova's lab identified the one of these enzymes that relates to fat accumulation: Aldehyde Dehydrogenase 1, or Aldh1a1.
Palifosfamide (Zymafos(R) or ZIO-201) is a novel DNA cross-linker that in preclinical study has been shown to bypass resistance mediated by aldehyde dehydrogenase (ALDH), in addition to conferring a favorable toxicity profile compared to other in-class agents.
Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme in ethanol metabolism.
Aof people from Asia lack the enzyme aldehyde dehydrogenase.
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