alcohol dehydrogenase

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Related to Alcohol metabolism: alcohol dehydrogenase

al·co·hol de·hy·dro·gen·ase (ADH),

(al'kŏ-hol dē-hi-droj'e-nās),
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the hydride acceptor; for example, ethanol + NAD+ ⇄ acetaldehyde + NADH.
See also: alcohol dehydrogenase (acceptor), alcohol dehydrogenase (NADP+).

alcohol dehydrogenase

/al·co·hol de·hy·dro·gen·ase/ (ADH) (de-hi´dro-jen-ās) an enzyme that catalyzes the reversible oxidation of primary or secondary alcohols to aldehydes; the reaction is the first step in the metabolism of alcohols by the liver.

alcohol dehydrogenase

Any of a class of enzymes that catalyze the oxidation of alcohols to aldehydes or ketones.

al·co·hol de·hy·dro·gen·ase

(ADH) (al'kŏ-hol dē-hī-droj'en-ās)
An oxidoreductase that reversibly converts an alcohol to an aldehyde (or ketone) with NAD+ as the H acceptor. For example, ethanol + NAD+↔ acetaldehyde+ NADH. Plays an important role in alcoholism.


an enzyme that mobilizes the hydrogen of a substrate so that it can pass to a hydrogen acceptor, such as NAD+ or FAD+.

alcohol dehydrogenase
dimeric enzyme protein of the liver catalyzing the NAD+-linked dehydrogenation of ethanol to acetaldehyde.
glucose-6-phosphate dehydrogenase
see glucose-6-phosphate dehydrogenase.
glutamate dehydrogenase (GD), glutamic dehydrogenase
an enzyme that catalyzes the reversible reaction of glutamic acid into 2-oxoglutaric acid and ammonia. High concentrations occur in the liver of sheep, cattle, horses and dogs. Serum levels are useful in detecting hepatocellular damage in ruminants.
l-iditol dehydrogenase (ID)
a liver specific enzyme; serum determinations have been used in the horse to detect hepatocellular damage. Called also sorbitol dehydrogenase, SDH.
isocitrate dehydrogenase (ICD)
an enzyme found in high concentrations in many tissues. Two major forms of the enzyme, an NAD+-dependent ICD associated with the mitochondrial TCA cycle and a NADP+-dependent ICD associated with fat synthesis in adipose tissue and lactating mammary gland of ruminants or with steroidogenesis in endocrine tissues. Serum levels have been used to detect hepatocellular damage, but it is not highly specific.
lactate dehydrogenase (LDH), lactic acid dehydrogenase
an enzyme that catalyzes the interconversion of lactate and pyruvate. It is widespread in tissues and is particularly abundant in kidney, skeletal muscle, liver and myocardium. It appears in elevated concentrations when these tissues are injured. See also mouse lactic dehydrogenase elevating virus.
lactate dehydrogenase agent
polyol dehydrogenase
sorbitol dehydrogenase (SDH)
References in periodicals archive ?
The two main enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH).
Because alcohol metabolism can significantly influence drinking behavior and the risk for alcoholism (Yin and Agarwal 2001), it is important to understand how genetic factors influence metabolism.
Each person's rate of alcohol metabolism is determined by the isoforms he or she carries.
Cytochrome P450 2E1 (CYP2E1), a protein that is part of the microsomal ethanol oxidizing system (MEOS) and is involved in alcohol metabolism primarily after chronic alcohol consumption.
Experiments with mice lacking the gene for ADH1 have revealed that ADH1 contributes to approximately 75 to 90 percent of alcohol metabolism (Deltour et al.
The consequences of alcohol metabolism include oxygen deficits (i.
Although the P450 pathway contributes a small amount to total alcohol oxidation (Lands 1998), the generation of ROS is significant as a result of the catalytic mechanism of the enzyme and is important to the generation of oxidative stress associated with alcohol metabolism.
As described in other articles in this journal issue, during alcohol metabolism in the liver, the alcohol (chemically known as ethanol) is first converted into acetaldehyde, a noxious compound.
The AER also can be used to examine the role of many other factors, such as recent food intake, lean body mass (LBM), liver blood flow, and menopausal changes in physiology, that contribute to variability in alcohol metabolism.
2005) indicated that there is an important site in the region containing the ADH genes that affects alcohol metabolism but is not related to the coding variations in ADH1B or ADH1C.
When social events and gatherings call for the consumption of adult beverages, a single DEFY[R] mix before, during or after social activities can enhance alcohol metabolism and help next-day mental alertness.
Many Japanese have a unique alcohol metabolism compared to the Caucasian population.