References in periodicals archive ?
The two main enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH).
Because alcohol metabolism can significantly influence drinking behavior and the risk for alcoholism (Yin and Agarwal 2001), it is important to understand how genetic factors influence metabolism.
Each person's rate of alcohol metabolism is determined by the isoforms he or she carries.
Cytochrome P450 2E1 (CYP2E1), a protein that is part of the microsomal ethanol oxidizing system (MEOS) and is involved in alcohol metabolism primarily after chronic alcohol consumption.
Experiments with mice lacking the gene for ADH1 have revealed that ADH1 contributes to approximately 75 to 90 percent of alcohol metabolism (Deltour et al.
The consequences of alcohol metabolism include oxygen deficits (i.
Although the P450 pathway contributes a small amount to total alcohol oxidation (Lands 1998), the generation of ROS is significant as a result of the catalytic mechanism of the enzyme and is important to the generation of oxidative stress associated with alcohol metabolism.
As described in other articles in this journal issue, during alcohol metabolism in the liver, the alcohol (chemically known as ethanol) is first converted into acetaldehyde, a noxious compound.
The AER also can be used to examine the role of many other factors, such as recent food intake, lean body mass (LBM), liver blood flow, and menopausal changes in physiology, that contribute to variability in alcohol metabolism.
2005) indicated that there is an important site in the region containing the ADH genes that affects alcohol metabolism but is not related to the coding variations in ADH1B or ADH1C.
When social events and gatherings call for the consumption of adult beverages, a single DEFY[R] mix before, during or after social activities can enhance alcohol metabolism and help next-day mental alertness.
Many Japanese have a unique alcohol metabolism compared to the Caucasian population.