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akathisia

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
akathisia /ak·a·this·ia/ (ak″ah-thĭ´zhah) a condition marked by motor restlessness, ranging from anxiety to inability to lie or sit quietly or to sleep, a common extrapyramidal side effect of neuroleptic drugs.
ak·a·this·i·a or ac·a·this·i·a (k-thz-)
n.
1. Motor restlessness characterized by muscular quivering and the inability to sit still, often a result of chronic ingestion of neuroleptic drugs.
2. Intense anxiety at the thought of sitting down; inability to sit down.

Akathisia
Agitated or restless movement, usually affecting the legs and accompanied by a sense of discomfort. It is a common side effect of neuroleptic medications.
Mentioned in: Schizophrenia

akathisia
[ak′əthē′zhə]
Etymology: Gk, a + kathizein, not to sit
a pathologic condition characterized by restlessness and agitation, such as an inability to sit still. akathisiac, adj.

akathisia [ak″ah-thĭ´zhah]
a condition of motor restlessness in which there is a feeling of muscular quivering, an urge to move about constantly, and an inability to sit still, a common side effect of neuroleptic drugs.

akathisia
Antsiness Neurology Motor restlessness ranging from a feeling of inner disquiet to inability to sit still or lie quietly, accompanied by a sensation of muscular quivering, and an urge to be in constant motion, a common extrapyramidal effect of neuroleptics/antipsychotics. See Extrapyramidal syndrome.


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No significant differences were found between the two study arms in scores on the Abnormal Involuntary Movement Scale, the Barnes Akathisia Rating Scale, or the Simpson Angus Scale.
In clinical practice, the term akathisia has been restricted to demonstrable motor restlessness, but if that is the only effect, it would have been called dyskinesia according to Healy, who cites four studies linking akathisia to both suicide and homicide.
One of the movement disorders, akathisia (unpleasant motor restlessness, often with a subjective irritability), seen with both FGAs and SGAs, could in fact contribute to aggression, whatever therapeutic effects the drugs are assumed to have; this might in part account for the greater numeric drop in MOAS score in the placebo group (although UBU scores in all groups were comparable).
 
 
 
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