NLRP3

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NLRP3

A gene located on chromosome 1q44 that encodes a pyrin-like protein that interacts with the apoptosis-associated speck-like protein PYCARD/ASC. NLRP3 has a caspase recruitment domain, and belongs to the NALP3 inflammasome complex; it plays a role in regulating inflammation and apoptosis.
 
Molecular pathology
NLRP3 mutations are associated with chronic infantile neurological cutaneous and articular (CINCA) syndrome, familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease (NOMID).
References in periodicals archive ?
As shown Figure 3, nuclear extracts from PMA-stimulated EL4 T cells (treated with AII fraction) and nuclear extract from nonstimulited EL4 T cells (treated with Sill fraction) exhibited strong NF-AT-binding activity in the electrophoretic mobility shift assays using a labeled oligonucleotide containing a consensus NF-AT site.
Figure 3 Differences in the Percent of Elderly Medicare+Choice Enrollees with IHD and CHF Reporting Diabetes, Stroke, or COPD/Asthma Compared to AII M+C Enrollees: 1998 Male Female Diabetes AII 18 14 IHD 26 25 CHF 34 31 Stroke AII 9 7 IHD 16 17 CHF 22 20 Asthma/COPD AII 13 12 IHD 17 19 CHF 25 25 NOTE: IHD is ischemic heart disease; CHF is congestive heart failure; and COPD is chronic obstructive pulmonary disease.
The Aii Sector ETFs are issued by Valuestream Investment Management (ACN 099 107 034) (AFSL No 246621) ('VIML') under a Product Disclosure Statement ('PDS') for the Aii Sector ETFs.
AII will address all forms of infrastructure improvement; from agriculture to telecom, energy to environmental sustainability, AII will work to craft solutions with public and private partners across the entire range of systems that hold our country C and world C together.
With virtually all of the technical aspects of integration automated behind the scenes, Aii eliminates as much as 90% of the time normally required to implement integrations.
The certified CoLOS Exchange interface creates a standard, multi-purpose solution, providing flexible RFID middleware on the plant floor and a stand-alone high speed RFID applicator for the SAP AII platform.
Of the total proceeds, approximately $115 million was contributed to AmTrust's insurance operations with approximately $50 million allocated to AII and approximately $50 million contributed to Technology in support of planned growth initiatives with the balance related to the purchase of Wesco.
Tenders are invited for Aii Div- Electrical Work Due To Provision Of Providing Five Room~s Of Two Bed Capacity Along With Kitchen & Furnishing With Centralized Cooling In Running Room At Marwar Junction.
To further its commitment to deliver SAP-centric solutions, PEAK has recently achieved two highly acclaimed SAP certifications: PEAK Automation Controller for RFID is "Certified for SAP NetWeaver" to interface to SAP AII (Auto ID Infrastructure) and is also a certified "Powered by SAP NetWeaver" product.
Additionally, the findings showed that the 250 mg and 500 mg doses of PS433540 were at least as effective in blocking the AII response as irbesartan, a leading angiotensin receptor blocker for the treatment of hypertension.
Analysing the avaialablity of sources to compute the 22 indicators of AII at local level.
As an RFID pioneer and leader, Zebra has been an ideal development partner in bringing AII v2.