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Agonist |
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agonist /ag·o·nist/ (ag´ah-nist) 1. one involved in a struggle or competition. 2. agonistic muscle. 3. in pharmacology, a drug that has an affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances.
Agonist A medication that has an affinity for and stimulates the activity of cell receptors that are normally stimulated by naturally occurring substances, including melatonin. agonist (aˑ·g n a muscle that, upon contraction, is balanced by the contraction of a different muscle. Also called prime mover. agonist (ag´ n 1. an organ, gland, muscle, or nerve center that is so connected physiologically with another that the two function simultaneously in forwarding a given process, such as when two muscles pull on the same skeletal member and receive a nervous excitation at the same time. Opposite: antagonist. 2. a drug or other substance having a specific cellular affinity that produces a predictable response. agonist 1. in physiology a muscle which in contracting to move a part is opposed by another muscle (the antagonist). 2. in pharmacology, a drug which has affinity for the cellular receptors of another drug or natural substance and which produces a physiological effect. adrenergic agonist (2) see adrenergic agents. cholinergic agonist (2) see cholinergic. partial agonist (2) a drug that combines with the relevant receptors but not with the efficiency of the agonist. agonist Pharmacology A substance that promotes a receptor-mediated biologic response, often by competing with another substance at the same receptor. Cf Antagonist. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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? Mentioned in | ? References in periodicals archive | ||
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Crystal structure of a mutant hERalpha ligand-binding domain reveals key
structural features for the mechanism of partial agonism. Theory must therefore
intervene in the agonism between the local and the general, the
empirical and the conceptual, the instance and the institution, in a
strategy of realignment or rearticulation that can negotiate
polarizations without acceding to their foundational claims, or being
caught within their binary representations. anti-cancer activity) and agonism (ie bone health)
became a real therapeutic possibility. |
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