agglutination /ag·glu·ti·na·tion/ (ah-gloo″tĭ-na´shun)
agglutination
agglutination (
glōō´tinā´shn),
agglutination
1. the action of an agglutinant substance.
2. the process of union in wound healing.
3. the clumping together in suspension of antigen-bearing cells, microorganisms, or particles in the presence of specific antibodies (agglutinins).agglu´tinative
cross agglutination the agglutination of particulate antigen by antibody raised against a different but related antigen; see also group a.
group agglutination agglutination of members of a group of biologically related organisms or corpuscles by an agglutinin specific for that group.
intravascular agglutination clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell aggregation.
ag·glu·ti·na·tion ( -gl t n-  shn)n. 1. The act or process of agglutinating. 2. The clumping together of red blood cells or bacteria, usually in response to a particular antibody. 3. A clumped mass of material formed by agglutination. Also called agglutinate. 4. Adhesion of wound surfaces in healing. |
agglutination
[əglo̅o̅′tinā′shən]
Etymology: L, agglutinare, to glue
the clumping together of cells as a result of interaction with agglutinins. agglutinate, v.
agglutination (
glōō´tinā´shn),n the aggregation or clumping together of cells as a result of their interaction with specific antibodies called agglutinins, commonly used in blood typing and in identifying or estimating the strength of immunoglobulins or immune sera.
agglutination
aggregation of separate particles into clumps or masses; especially the clumping of bacteria or blood cells by antibody specific to, or directed against, surface antigenic determinants. See also agglutinin.
bacterial agglutination test
a diagnostic procedure that employs serum or other body fluid of unknown antibody titer, titrated with standard suspension of bacteria as antigen. These may be performed quantitatively in 96-well microtitration plates or qualitatively on slides.
cross agglutination
the agglutination of particulate antigen by an antibody raised against a different but related antigen; see also group agglutination (below).
group agglutination
agglutination—usually to a lower titer—of various members of a group of biologically related organisms by an agglutinating antibody made to one of that group.
intravascular agglutination
clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell agglutination.
latex agglutination test
see passive agglutination test (below).
microscopic agglutination test
one in which the test mixtures are examined microscopically to detect the agglutination.
mucus agglutination test
see mucus agglutination test.
passive agglutination test
an agglutination reaction in which a soluble antigen, such as gonadotropin, is linked to inert particles such as latex beads or tanned erythrocytes.
platelet agglutination
the clumping together of platelets owing to the action of platelet agglutinins. Such agglutinins are important in platelet typing.
slide agglutination test
a rapid screening or semiquantitative test in which antibody and antigen are mixed on a glass slide and observed for agglutination.
agglutination test
see bacterial agglutination test (above).
tube agglutination test
an agglutination test for the identification of bacteria carried out in a test tube, a positive reaction consisting of a clearing of a prior opalescence.
agglutination
Lab medicine The clumping of aggregates of antigens or antigenic material-eg bacteria, viruses, with antibodies in a solution. See Latex agglutination test Reproductive biology The conjoining of 2 organisms of the same species
for sexual reproduction, which may be mediated by a carbohydrate on one organism and a protein on the other, thereby forming a glycoprotein.
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