| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,770,115,101 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
agammaglobulinemia |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia | 0.01 sec. |
|
agammaglobulinemia /agam·ma·glob·u·lin·emia/ (a-gam″ah-glob″u-lĭ-ne´me-ah) absence of all classes of immunoglobulins in the blood. See also hypogammaglobulinemia. X-linked agammaglobulinemia an X-linked disorder characterized by absence of circulating B lymphocytes, plasma cells, or germinal centers in lymphoid tissues, very low levels of circulating immunoglobulins, susceptibility to bacterial infection, and symptoms resembling rheumatoid arthritis; apparently due to failure of pre-B cells to differentiate into mature B cells.
Agammaglobulinemia The lack of gamma globulins in the blood. Antibodies are the main gamma globulins of interest, so this term means a lack of antibodies. Mentioned in: Immunodeficiency agammaglobulinemia [agam′əglob′yo̅o̅linē′mē·ə] Etymology: Gk a + gamma, not gamma (third letter of Greek alphabet); L, globulus, small sphere; Gk, haima, blood the absence of the serum immunoglobulin gamma globulin, associated with an increased susceptibility to infection. The condition may be transient, congenital, or acquired. The transient form is common in infancy before 6 weeks of age, when the infant becomes able to synthesize the immunoglobulin. The congenital form is rare and sex-linked, affecting male children; it results in decreased production of antibodies. The acquired form usually occurs in malignant diseases such as leukemia, myeloma, or lymphoma. Also spelled agammaglobulinaemia. See also Bruton's agammaglobulinemia, immune gamma globulin. agammaglobulinemia (āˈ·gaˈ·m n condition in which the serum immunoglobulin gamma globulin is absent, thus increasing risk of infection. Can be fleeting, hereditary, or acquired. agammaglobulinemia severe or complete deficiency of immunoglobulins (antibodies) in the blood. Due to reliance on colostral versus placental transfer of immunoglobulins most domestic animals are agammaglobulinemic at birth, prior to suckling. An inherited defect is not commonly recorded in animals, but does occur as a primary inherited condition and as part of a combined immune deficiency, both of them in horses. The deficiency or absence of antibodies results in severe and recurrent infections. See also hypogammaglobulinemia, combined immune deficiency syndrome (disease). Bruton's agammaglobulinemia an inherited, X-linked recessive condition in humans involving a deficiency of B lymphocytes and plasma cells. A similar condition, though less well characterized, has been recognized in horses. agammaglobulinemia 1 Swiss agammaglobulinemia, see there 2 X-linked agammaglobulinemia, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in | ? References in periodicals archive | |
|---|---|---|
Persistent and fatal central nervous system
echovirus infections in patients with agammaglobulinemia. Among the possible treatments are the elimination of chronic
sinusitis, avoidance of or desensitization to offending allergens,
repair of a cleft palate, treatment of agammaglobulinemia, or
tonsillectomy and adenoidectomy. These disorders encompass more than 100 diseases, including
common variable immunodeficiency, X-linked agammaglobulinemia, and
severe combined immunodeficiency. |
| Medical Dictionary |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|