Bantu siderosis

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Bantu siderosis

Excessive iron stores in the body due to a large intake of beer prepared in iron pots. The condition can lead to CIRRHOSIS of the liver.
References in periodicals archive ?
Hereditary hemochromatosis must be distinguished from other conditions that cause iron overload, such as porphyria cutanea tarda, [beta]-thalassemia, medicinal and transfusional iron overload, and African iron overload (46).
In these populations, African iron overload has been attributed to high iron intake via the consumption of a traditional alcoholic beverage that is brewed in nongalvanized iron utensils (8, 9).
In this study, we reexamined iron status according to TF phenotype in the general population and, in particular, in subjects at risk of African iron overload.
In African iron overload, heterozygous TF CD individuals might be partly protected from increased iron accumulation.
Individuals with increased TS values were selected because they may potentially have an iron-loading condition such as hereditary hemochromatosis, African iron overload, or one of the various forms of secondary iron overload.
Is there a link between African iron overload and the described mutations of the hereditary haemochromatosis gene?
The subjects were 178 volunteers from rural Swaziland and rural Zimbabwe, who were studied from 1993 to 1995 as part of an investigation of families with African iron overload and of community members with a history of traditional beer consumption.
Eighty-eight of the subjects were enrolled as part of a study of families with African iron overload, and 62 subjects were enrolled as part of a study of community members with a history of traditional beer consumption.
In the present study, we provide evidence that circulating transferrin receptor concentrations are inversely and significantly proportional to indirect measures of the size of the body's iron stores, and that receptor concentrations are significantly less in subjects with African iron overload than in normal and iron-deficient subjects.
Sideroblastic anemia Hereditary atransferrinemia Porphyria cutanea tarda Neonatal hemochromatosis Transfusional iron overload African iron overload [beta]-Thalassemia Postportocaval shunt X-linked iron-loading anemia Chronic hemodialysis Pyridoxine-responsive anemia Medicinal iron overload Pyruvate kinase deficiency Table 2.
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