advanced glycation endproducts

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advanced glycation endproducts

; AGEs formation of endproducts of non-enzymatic protein lipoproteins and nucleic acid glycosylation; exaggerated in old age, but accelerated in poorly controlled diabetes mellitus; AGEs accumulate in structural proteins (of ligaments, blood vessel walls, etc.) to compromise the microcirculation, especially within skin, vasa vasorum and vasa nervosum, contributing to the secondary complications of long-term diabetes, i.e. loss of joint mobility, neuropathy and ischaemia (see glycosylated haemoglobin; glycosylation)
References in periodicals archive ?
MG is a type of advanced glycation endproduct (AGEs), which is produced when food is cooked with dry heat.
Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease.
Body weight, blood glucose, endothelium-dependent/-independent relaxation, vasocontraction by free radical-induced and contractive prostanoids, triglyceride, advanced glycation endproduct, lipid peroxides, serum N[O.
The advanced glycation endproduct CIVIL is a product both of lipid peroxidation and glycoxidation reactions J Biol Chem 1996;271:9982-6.
Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation endproduct, tissue factor and TNF-alpha.
established in 2004 as an independent spinout of InLight Solutions, is applying its proprietary Spectroscopic Advanced Glycation Endproduct (SAGE) detection technology to develop the SCOUT DS system -- intended to be the first non-invasive diabetes screening system that provides healthcare professionals with an accurate and convenient method for detecting type 2 diabetes and pre-diabetes based on the presence of advanced glycation endproduct biomarkers found in skin.
based in Albuquerque, New Mexico, is a privately held medical instrumentation company applying its proprietary Spectroscopic Advanced Glycation Endproduct (SAGE) detection technology to develop Scout DS -- the first non-invasive diabetes screening system that provides health care professionals with a more accurate and convenient method for detecting type 2 diabetes and pre-diabetes based on the presence of biomarkers found in skin.
Protective effects of Comi fructus against advanced glycation endproducts and radical scavenging.
However, they tend to only focus on their cholesterol, blood pressure, and body mass index (BMI), and overlook another key medical marker: Advanced Glycation Endproducts (AGEs).
They are also involved in the formation of advanced glycation endproducts (AGEs), which contribute to DNA lesions.
Other than a monitor of glucose concentrations, glycation is a precursor to the formation of intracellular and plasmaborne advanced glycation endproducts (AGEs) that are found to accumulate in arterial and microvascular plaques (28).

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