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adult T-cell leukemia-lymphoma |
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adult T-cell leukemia-lymphoma
Oncology A rapidly-progressive lymphoproliferative malignancy of mature T lymphocytes, commonly associated with infection by the retrovirus, HTLV-I, first described in southeastern Japan, also seen in the
Caribbean, Africa and in blacks in the southeastern US, in whom the disease is aggressive with skin lesions, hypercalcemia, rapid enlargement of hilar, retroperitoneal and peripheral lymph nodes with mediastinal sparing, invasion of CNS, lungs, GI
tract, opportunistic infections–eg, Pneumocystis carinii. See T-cell lymphoma
Adult T-cell leukemia-lymphoma–clinical forms
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