Adriamycin


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Related to Adriamycin: Taxol

Adriamycin

 [a″dre-ah-mi´sin]
trademark for preparations of doxorubicin, an antineoplastic antibiotic.

dox·o·ru·bi·cin

(doks'ō-rū'bi-sin),
An antineoplastic antibiotic isolated from Streptomyces peucetius; also used in cytogenetics to produce Q-type chromosome bands.
Synonym(s): adriamycin

Adriamycin

/Adri·a·my·cin/ (a″dre-ah-mi´sin) trademark for preparations of doxorubicin hydrochloride.

Adriamycin

(ā′drē-ə-mī′sən)
A trademark for the drug doxorubicin.

Adriamycin

An anthracycline antibiotic with antineoplastic activity, which is used to treat haematologic malignancies, especially leukaemias, but also carcinomas and solid tumours (for which it is not particularly effective); its efficacy is hampered by cardiotoxicity that increases as the cumulative dose passes 500 mg/mm3.
Adverse effects Nausea, vomiting, neutropenia; about one-fourth of Adriamycin-treated patients develop late cardiac abnormalities once the cumulative dose passes 450 mg/mm2 including cardiac failure, dysrhythmia and sudden death; post-mortem examination of the heart reveals myocardial fibrosis.

adriamycin

Doxorubicin HCl Oncology An anthracycline antibiotic with antineoplastic activity, used to treat both leukemia and solid tumors; its efficacy is hampered by cardiotoxicity that ↑ as the cumulative dose passes 500 mg/mm3

Adriamycin

Doxorubicin. An anticancer drug which acts by interfering with cell division.

adriamycin,

n an antineoplastic agent used in cancer treatment.

adriamycin

doxorubicin.
References in periodicals archive ?
A clinicopathologic analysis of adriamycin cardiotoxicity.
2000), while adriamycin induces frameshift and GC to AT transition events (Mackay & Phelps 2001).
Even in the world of toxic chemotherapy, Adriamycin and its fellow anthracyclines are notoriously dangerous: Slamon and Press refer to the "well-known, long-term, and life-threatening problems associated with anthracyclines.
As reference substances mistletoe lectin I (ML-1), adriamycin and interleukin-6 (IL-6) were used.
A diagnosis of multiple myeloma was established, and he was started on a regimen of vincristine, Adriamycin, dexamethasone and pamidronate.
Of 1,477 women who participated in the randomized, controlled trial (all of whom were postmenopausal, had axillary lymph node involvement, and had tumors with either estrogen or progesterone receptors), 566 were treated with 6 months of chemotherapy (cyclophosphamide, Adriamycin, and 5-fluorouracil) followed by 5 years of tamoxifen, she said.
Adriamycin (doxorubicin hydrochloride), dimethyl sulfoxide (DMSO), ICR 191 acridine mutagen (6-chloro-9-[3-(2-chloroethylamino)propylamino]-2-methoxyacridine), [N.
The patient received 6 courses of chemotherapy with full doses of cyclophosphamide (1100 mg), adriamycin (75 mg), vincristine (2 mg), and prednisone (100 mg) supplemented with Neupogen and Epogen.
When taken with the chemotherapy drugs Adriamycin and Cytoxin, Herceptin resulted in a 50 percent or greater measurable breast cancer reduction in 52 percent of patients.