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Epinephrine |
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epinephrine /epi·neph·rine/ (-nef´rin) a catecholamine hormone secreted by the adrenal medulla and a central nervous system neurotransmitter released by some neurons. It is stored in chromaffin granules and is released in response to hypoglycemia, stress, and other factors. It is a potent stimulator of the sympathetic nervous system (adrenergic receptors), and a powerful vasopressor, increasing blood pressure, stimulating the heart muscle, accelerating the heart rate, and increasing cardiac output. It is used as a topical vasoconstrictor, cardiac stimulant, systemic antiallergic, bronchodilator, and topical antiglaucoma agent; for the last two uses it is also administered as the bitartrate salt. Called also adrenaline (Great Britain).
Epinephrine Also called adrenalin, a secretion of the adrenal glands (along with norepinephrine) that helps the liver release glucose and limits the release of insulin. Norepinephrine is both a hormone and a neurotransmitter, a substance that transmits nerve signals. epinephrine (eh·pi·neˑ·frin), n neurochemical produced by the adrenal glands that arouses the sympathetic response. Also called adrenaline. epinephrine (ep´inef´rin), n a hormone secreted by the adrenal medulla that stimulates hepatic glycogenolysis, causing an elevation in the blood sugar, vasodilation of blood vessels of the skeletal muscles, vasoconstriction of the arterioles of the skin and mucous membranes, relaxation of bronchiolar smooth muscles, and stimulation of heart action. Used in local anesthetics for its vasoconstrictive action to prolong the anesthesia action, provide hemostasis, and reduce systemic complications. epinephrine/epinephrine bitartrate/epinephrine HCl, n brand names: EpiPen Jr., Bronkaid Mist, Primatene Mist; drug class: adrenergic agonist, catecholamine; action: β1- and β2-agonist, causing increased levels of cAMP, producing bronchodilation and cardiac stimulation; uses: acute asthmatic attacks, hemostasis, bronchospasm, anaphylaxis, allergic reactions, cardiac arrest, vasopressor. Recommended for the dental office or clinic emergency kit. See EpiPen. epinephrine a hormone produced by the medulla of the adrenal glands; called also adrenaline. Its function is to aid in the regulation of the sympathetic branch of the autonomic nervous system. At times when an animal is highly stimulated, as by fear, anger or some challenging situation, extra amounts of epinephrine are released into the bloodstream, preparing the body for energetic action. Epinephrine is a powerful vasopressor which increases blood pressure and increases the heart rate and cardiac output. It also increases glycogenolysis and the release of glucose from the liver. |
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