In laboratory studies, animals with EAE (experimental allergic encephalomyelitis, a disease that causes MS-like symptoms) were given specially engineered antibodies designed to make the adhesion molecules
The intra- and interassay CVs for the adhesion molecules
were as follows: ICAM-1, 6.
Monoclonal antibodies to adhesion molecules
created; they stop immune ceils from crossing blood-brain barrier, which prevents EAE in lab animals (1992)
Ros' research shows that substituting walnuts for monounsaturated fat in a Mediterranean diet improved, and even restored, endothelial function, as well as reduced cell adhesion molecules
associated with atherosclerosis, commonly known as hardening of the arteries.
After eight weeks, the overweight individuals experienced increased insulin sensitivity and decreased levels of endothelial adhesion molecules
Serum levels of soluble adhesion molecules
in chronic renal failure and dialysis patients.
Effective stroke therapies must alleviate ischemic damage induced by blocked blood flow to the brain and also prevent the progressive tissue damage and swelling of the brain caused by invading adhesion molecules
, neutrophils and inflammatory cytokines.
Previous studies have shown that merozoites place proteins on the surfaces of the red cells they infect and that the proteins bind to so-called cell adhesion molecules
on other cells (SN: 6/13/92, p.
Finally, treatment of the cells with PLE prevented UV-induced morphological changes in human fibroblasts, namely disorganisation of F-actin-based cytoskeletal structures, coalescence of the tubulin cytoskeleton and mislocalization of adhesion molecules
such as cadherins and integrins.
Researchers describe its application to such matters as the molecular mechanism of secretory vesicle content expulsion during cell secretion, the plant cell wall and its constituents, cellular interactions of nanoscale drug deliver systems, inter-molecular forces of leukocyte adhesion molecules
, and imaging soft surfaces.
9 million from Boehringer Ingelheim to support Isis' research and development activities in conjunction with the companies' collaboration to discover and commercialize drugs to treat inflammatory diseases by inhibiting cell adhesion molecules
Several different classes of these cell adhesion molecules
, or CAMs, form the appendages cells use to clasp each other and to grip the scaffolding of connective fibers that laces organized tissues and organs.