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adeno-associated virus |
Also found in: Acronyms, Wikipedia | 0.04 sec. |
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adeno-associated virus a replication-defective, single-stranded DNA virus classifed in the genus Dependovirus of the family Parvoviridae. They depend on help provided by coinfection with adenoviruses for their replication. Not known to cause disease. |
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? Mentioned in | ? References in periodicals archive | |
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Recombinant adeno-associated virus gone therapy
for cystic fibrosis and [alpha]1-antitrypsin deficiency. High and her team injected the adeno-associated virus loaded with
the factor IX gene into the leg muscles of five hemophiliac dogs. In this Phase I trial of AAT gene therapy, Brantly, Flotte and
colleagues at the University of Florida, Gainesville, injected
increasing doses of recombinant adeno-associated virus serotype 2
(rAAV2)-AAT vector into 12 AAT-deficient adults. |
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adeno-associated virus
