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adeno-associated virus |
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adeno-associated virus a replication-defective, single-stranded DNA virus classifed in the genus Dependovirus of the family Parvoviridae. They depend on help provided by coinfection with adenoviruses for their replication. Not known to cause disease. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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Recombinant adeno-associated virus gone therapy
for cystic fibrosis and [alpha]1-antitrypsin deficiency. High and her team injected the adeno-associated virus loaded with
the factor IX gene into the leg muscles of five hemophiliac dogs. In this Phase I trial of AAT gene therapy, Brantly, Flotte and
colleagues at the University of Florida, Gainesville, injected
increasing doses of recombinant adeno-associated virus serotype 2
(rAAV2)-AAT vector into 12 AAT-deficient adults. |
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