nifedipine

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nifedipine

 [ni-fed´ĭ-pēn]
a calcium channel blocking agent administered orally as a coronary vasodilator in the treatment of angina pectoris; also used in the treatment of hypertension.

nifedipine

/ni·fed·i·pine/ (ni-fed´ĭ-pēn) a calcium channel blocking agent used as a coronary vasodilator in the treatment of coronary insufficiency and angina pectoris; also used in the treatment of hypertension.

nifedipine

(nī-fĕd′ə-pēn′)
n.
A calcium channel blocker drug, C17H18N2O6, that acts as a coronary vasodilator and is used primarily to treat hypertension and angina pectoris.

NIFEdipine

[nifed′ipēn]
a calcium channel blocker.
indications It is prescribed for the treatment of vasospastic and effort-associated angina, pulmonary hypertension, and hypertension (sustained-release form only).
contraindications Known hypersensitivity to this drug prohibits its use, and immediate-release forms should not be used to treat hypertension. The practice of using short-acting sublingual nifedipine in hypertensive emergencies or pseudoemergencies is dangerous and should be abandoned.
adverse effects Among the more serious adverse effects are hypotension, peripheral edema, palpitations, dyspnea, nausea, dizziness, flushing, and headache. When given sublingually, stroke, severe hypotension, syncope, heart block, sinus arrest, myocardial infarctions, and fetal distress are among the adverse effects reported.

nifedipine

Procardia® Cardiology A dihydropiridine CCB vasodilator used for angina, as a short-acting antihypertensive–↓ BP, resulting in a ↓ left ventricular volume and myocardial mass, ↑ ejection fraction Side effects Tachycardia, headache, peripheral edema, cerebral ischemia, stroke, severe hypotension, AMI, conduction defects, fetal distress, death. See Calcium channel blockers, Hypertension, TIBBS.

nifedipine

A CALCIUM CHANNEL BLOCKER drug used to control the symptoms of ANGINA PECTORIS and to treat high blood pressure (HYPERTENSION). It has a powerful effect in widening (dilating) arteries, including the coronary arteries, and this improves the blood supply to the heart muscle. The drug, however, causes flushing, headache, skin itching and dizziness. It is often used in combination with a BETA-BLOCKER. Nifedipine has been used effectively to prevent high altitude lung oedema, a feature of mountain sickness. The drug is on the WHO official list. Brand names are Adalat, Adipine MR, Angiopine MR, Cardilate MR, Coracten, Fortipine LA, Tensipine MR and Unipine XL.

nifedipine

calcium channel-blocking drug; may be used to treat severe perniosis, or to control pain of leiomyoma

nifedipine (nīfed´əpēn´),

n brand names: Procardia, Procardia XL;
drug class: calcium channel blocker;
action: inhibits calcium ion influx across cell membrane during cardiac depolarization; produces relaxation of coronary vascular smooth muscle, dilates coronary arteries; increases myocardial oxygen delivery in patients with vasospastic angina; dilates peripheral arteries;
uses: chronic stable angina pectoris, vasospastic angina, hypertension. Can cause gingival hyperplasia.

nifedipine

a calcium channel blocker used principally as a vasodilator.
References in periodicals archive ?
Biovail was the first company to file an abbreviated new drug application ("ANDA") with the FDA for the 60mg strength of Adalat CC and will be entitled to 180 days of marketing exclusivity.
D) BAYER agreed to settle its civil liabilities to the Public Health Service entities in an amount of at least $9,482,620, in civil damages for losses suffered by those entities as a result of BAYER overcharging for Cipro and Adalat CC because the prices for those drugs were determined in part by prior Medicaid rebates that were underpaid because the best price was under- reported.
R&D spending during third quarter 1996 was unusually high due to accomplishment of a number of key milestones in development of generic forms of Imdur and Adalat CC for Warner Chilcott by Elan Corporation, plc.
The 30mg dosage strength represents approximately 35% of total Adalat CC brand sales.
Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Nifedipine Extended-release Tablets USP, 30 mg, 60 mg and 90 mg, the generic version of Bayer's Adalat CC Tablets, a treatment for hypertension.
Federal Trade Commission (the "FTC") resolving the FTC's investigation of a licensing arrangement between Elan and Biovail Corporation ("Biovail") relating to nifedipine, the generic version of the hypertension drug Adalat CC.
s Reglan (nausea), Kadian (acute pain), and Bayer's (OTC: BAYRY) Adalat CC (hypertension and angina) among others.
Bayer Pharmaceuticals sells Adalat CC, the branded form of an extended-release nifedipine tablet that is usually taken once a day.
Elan Corporation, plc (Dublin, Ireland; 0902-4666) announced that on May 12, 2000 the United States Court of Appeals for the Federal Circuit ("CAFC") issued a decision affirming an earlier court judgment that Elan's Nifedipine Extended-Release tablets (30 mg), a generic equivalent to Bayer's hypertension drug Adalat CC, does not infringe Bayer AG's United States Patent 5,264,446.
Additionally, incremental 2002 product sales revenues versus 2001 have been favorably impacted by the launch of a bioequivalent version of Adalat CC 90mg and strong sales via the Company's Canadian sales and marketing organization.
Nifedipine ER is the generic version of Bayer AG's Adalat CC product and is indicated for the treatment of hypertension.
During the year, we successfully launched our generic versions of Cardizem CD and Verelan and we received tentative approval for our generic version of Adalat CC.