Koshland-Nemethy-Filmer model

(redirected from Adair-Koshland-Nemethy-Filmer Model)
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Kosh·land-Né·meth·y-Fil·mer mod·el (KNF mod·el),

(kosh'lănd nem'ĕ-thē fil'mĕr),
an explanation of the allosteric form of cooperativity. In this model, in the absence of ligands, the oligomeric protein exists in only one conformation; on binding, the ligand induces a conformational change that may be transmitted to other subunits.
[Daniel E. Koshland, George Némethy, David L. Filmer]

Filmer,

David L., U.S. biochemist, 1932–.
Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer model
Koshland-Némethy-Filmer model - see under Koshland

Koshland,

Daniel E., U.S. biochemist, 1920–.
Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer model
Koshland-Némethy-Filmer model - a model to explain the allosteric form of cooperativity. Synonym(s): Adair-Koshland-Némethy-Filmer model; induced fit model

Némethy,

George, Hungarian-U.S. biochemist, 1934–.
Adair-Koshland-Némethy-Filmer model - Synonym(s): Koshland-Némethy-Filmer model
Koshland-Némethy-Filmer model - see under Koshland