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transplant rejection |
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transplant 1. an organ or tissue taken from the body and grafted into another area of the same individual or another individual. 2. to transfer tissue from one part to another or from one individual to another. ovum transplant see ovum transplant. transplant rejection see rejection. transplant rejection Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by optimal
matching of MHC antigens and ABO blood groups and ameliorated with immunosuppressants–eg, cyclosporin, tacrolimus, rapamycin Exceptions of TR Corneal transplants, identical twins. See Graft-versus-host disease, HLA, MHC, Tissue typing. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The primary clinical endpoint
is defined as the occurrence of acute transplant rejection, graft loss,
or death within 6 months post-transplant. Complications associated with
ischemia/reperfusion injury include delayed function of the transplanted
kidney, acute transplant rejection, and chronic kidney dysfunction. Acute transplant rejection occurs when cells of the immune system
recognize the transplanted organ as foreign and attack it as a potential
threat. |
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