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Acute phase reactant

   Also found in: Wikipedia 0.01 sec.
Acute phase reactant
A substance in the blood that increases as a response to an acute conditions such as infection, injury, tissue destruction, some cancers, burns, surgery, or trauma.


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Acute phase reactants for inflammation such as the ESR and CRP will invariably be abnormal.
They cover the translational and transcriptional regulation of inflammation, molecular components of inflammation and inflammatory mediators, cellular components of inflammation, leukocytes, microglia and macrophages, interactions between microglia and astrocytes, the systemic inflammatory response, and acute phase reactants.
CRP is a nonspecific acute phase reactant protein that amplifies the inflammatory cascade, and concentrations increase in the serum in response to inflammatory stimuli.
 
 
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