acute phase protein

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acute phase protein

plasma proteins associated with inflammation including C-reactive protein (CRP), mannose-binding protein, serum amyloid P component, α1-antitrypsin, fibrinogen, ceruloplasmin, and complement components C9 and factor B, the concentrations of which increase in response to interleukins 1, 6, and 11.

acute phase protein

Any of the plasma proteins whose concentration increases or decreases by at least 25% during inflammation. Acute-phase proteins include C-reactive protein, several complement and coagulation factors, transport proteins, amyloid, and antiprotease enzymes. They help mediate both positive and negative effects of acute and chronic inflammation, including chemotaxis, phagocytosis, protection against oxygen radicals, and tissue repair. In clinical medicine the erythrocyte sedimentation rate or serum C-reactive protein level sometimes is used as a marker of increased amounts of acute-phase proteins. Synonym: acute phase reactant See: inflammation
See also: protein
References in periodicals archive ?
In its acute phase, this stage can last for days or weeks.
The team members from the acute phase of care came to understand the important rehabilitation concepts that needed to be integrated into the acute care of the patient.
We're all too familiar with the aftermath of the acute phase of a cold.
RapiPlex, is a novel, user-friendly, cost effective, multiplexing point of care in vitro diagnostics platform that gives access to a broad range of diagnostic applications including acute phase diagnostics, prognostic diagnostic panels and companion diagnostics at the point of care.
Knowing your numbers means a patient will understand their own acute phase response to infection or inflammation not requiring the comparison against normal ranges for diagnosis.
Most virus infections resolve after an acute phase.
They found that two of the markers are Acute Phase Proteins (APP's).
Maintenance of effect was assessed in the responders - 58 duloxetine patients who had experienced at least 30 percent pain reduction from baseline during the 13-week, placebo-controlled acute phase of the study.
During the acute phase of treatment, a combination of psychotherapy and drug therapy was consistently more effective than either therapy alone; the number needed to treat ranged from 7 to 10 patients.
She counsels against crunches and sit-ups during the acute phase.
TOS comprises three phases: the early acute phase, an intermediate phase involving neurologic complaints and intense muscle pain, and, for approximately 60% of victims, a chronic phase marked by motor and sensory nerve disorders and muscle pain and cramping.
Mr de Rooy admitted donations had suffered because of anti-war fellings but said: "Now is time to come forward with resources so the UN can play a role in the acute phase of this crisis.

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