acute interstitial nephritis

acute interstitial nephritis.

See interstitial nephritis.

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acute interstitial nephritis

Acute allergic nephritis Nephrology Renal inflammation characterized by cellular—primarily mononuclear—and fluid exudates, often with epithelial degeneration Types Idiopathic, 2º to drugs or infections Findings-hypersensitivity Fever, rash, sore throat, malaise, arthralgia, myalgia, hepatitis, splenomegaly, eosinophilia, lymphoadenopathy, thrombocytopenia, autoimmune hemolysis Findings-anaphylaxis Respiratory tract–laryngeal edema, asthma; skin–urticaria, angioedema; GI tract–N&V, diarrhea; cardiovascular–capillary leak, hypotension Lab-Proximal tubule Glycosuria, aminoaciduria, tubular proteinuria–usually < 1 g/24 h, hypouricemia Distal tubule Distal renal tubular acidosis, ↑ K+, isosthenuria, Na+ wasting Management Corticosteroids may be effective Prognosis From mild renal dysfunction to acute renal failure