acute HIV syndrome

(redirected from Acute HIV Infection)
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Acute HIV Syndrome

A transient, flu-like early response to HIV-1, that occurs 1 to 6 weeks after exposure to HIV-1 in 50%–70% of those with primary HIV infection. AHS presents as an acute infectious mononucleosis-like complex and is accompanied by viraemia and an immune response to HIV within 1 week to 3 months.
Clinical findings Fever, severe fatigue, sore throat, lymphadenopathy, anorexia, nausea, vomiting, and a maculopapular rash; less commonly, diarrhoea, lightning-like pain, major weight loss, abdominal cramping, palmoplantar desquamation, myalgia, arthralgia, headache, photophobia, pruritic or urticarial rash, lymphocytic meningoencephalitis and peripheral neuropathy, all symptoms remit, and reappear as AIDS after a latency of up to several years.
Lab Mild leukopaenia, occasionally inversion of the CD4:CD8 ratio, antibodies to HIV products—gp120, gp160, p24 and p41 first appear ≥ months after infection. The syndrome affects one-third of previously healthy heterosexual subjects but is uncommon in homosexual males.

acute HIV syndrome

Acute HIV infection, primary symptomatic HIV infection A transient, flu-like early response to HIV-1, that occurs 1-6 wks after exposure to HIV-1 in 50-70% of those with 1º HIV infection; AHS presents as an acute infectious mononucleosis-like complex and is accompanied by viremia and an immune response to HIV within 1 wk to 3 months Clinical Fever, severe fatigue, sore throat, lymphadenopathy, anorexia, N&V, and a maculopapular rash, less commonly, diarrhea, lightning-like pain, major weight loss, abdominal cramping, palmoplantar desquamation, myalgia, arthralgia, headache, photophobia, lymphadenopathy, pruritic maculopapular or urticarial rash, lymphocytic meningoencephalitis and peripheral neuropathy, all Sx remit, and reappear as AIDS after a latency of up to several yrs Lab Mild leukopenia, occasionally inversion of the CD4:CD8 ratio, antibodies to HIV products–gp120, gp160, p24 and p41 first appear ≥ months after infection. See AIDS, CD4:CD8 ratio, HIV-1.
References in periodicals archive ?
A laboratory in Sioux Falls, SD, detected three acute HIV infections.
This amounted to a prevalence of acute HIV infection of 2.
In light of the evidence for acute HIV infection and the exclusion of other causes of acute pancreatitis, his pancreatitis appears to be due to primary HIV infection.
The proposed algorithm promises to improve, first, the detection of acute HIV infection, and, second, differentiation between HIV-1 and HIV-2 infection, all with faster turnaround time.
Mascolini: Your work indicates that people with acute HIV infection don't understand the high transmission risk associated with their new infection.
During an epidemic, acute HIV infection should also be considered (8).
Approaching 'HIV elimination': interventions for acute HIV infection.
An increasing amount of data shows a significant immunologic benefit of early antiretroviral treatment in patients with acute HIV infection before seroconversion.
Routine screening of selected patients for acute HIV infection is edging closer toward becoming standard practice.
Augmentation of immune responses from STI has been clearly shown in treated acute HIV infection, and our own studies continue to show success in the majority of persons who have participated in a complicated STI trial.
She completed her internship and residency in Internal Medicine at the University of North Carolina, Chapel Hill, and was a Senior Fellow in Infectious Diseases at the University of Washington, Seattle, where she conducted research in HIV transmission and acute HIV infection.

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