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Active immunization

   Also found in: Dictionary/thesaurus, Legal, Financial, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
immunization /im·mu·ni·za·tion/ (im″u-nĭ-za´shun) the process of rendering a subject immune, or of becoming immune.
active immunization  stimulation with a specific antigen to induce an immune response.
passive immunization  the conferral of specific immune reactivity on previously nonimmune individuals by administration of sensitized lymphoid cells or serum from immune individuals.

Active immunization
Treatment that provides immunity by challenging an individual's own immune system to produce antibody against a particular organism, in this case the rabies virus.
Mentioned in: Rabies

immunization
the process of rendering a subject immune, or of becoming immune. See also vaccination.

active immunization
stimulation with a specific antigen to promote an immune response. In the context of infectious diseases, the antigenic substances may include: (1) inactivated bacteria, as in botulism immunization; (2) inactivated viruses, as in the canine parvovirus vaccination; (3) live attenuated viruses, e.g. rabies virus, and (4) toxoids, chemically treated toxins produced by bacteria, as in immunization against tetanus and pasteurellosis. Any of a vast number of foreign substances may induce an active immune response.
Since active immunization induces the body to produce its own antibodies and specifically reactive cells and to go on producing them, protection against disease will last several years, in some cases for life.
antihormone immunization
immunization against hormones, e.g. against androstenedione for the stimulation of ovulation in ewes, is now a commercial reality and promises to be a significant management tool in intensive animal production. See also immunological contraception.
deliberate immunization
the administration of an immunogen, usually by injection but sometimes orally or by inhalation, for the purpose of producing immunity.
natural immunization
stimulation of the immune system through exposure to antigens that have not been deliberately administered.
passive immunization
transient immunization produced by the introduction into the system of pre-formed antibody or specifically reactive lymphoid cells. The animal immunized is protected only as long as these antibodies or cells remain in the blood and are active—usually from 4 to 6 weeks. The immunity may be natural, as in the transfer of maternal antibody to offspring, or artificial, passive immunity following inoculation of antibodies or immune cells.


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Two strategies have evolved to reduce the disease burden in patients with bacterial meningitis: (1) active immunization against the most common pathogens and (2) reduction of central nervous system inflammation with anti-inflammatory therapy.
In fact, deliberate disruption of the GnRH system is the basis for using GnRH analogs in active immunization paradigms for contraceptive purposes (22).
Individuals with impaired immune responsiveness, whether due to the use of immunosuppressive therapy, a genetic defect, Human Immunodeficiency Virus (HIV) infection, or other causes, may have reduced antibody response to active immunization (see PRECAUTIONS, Drug Interactions).
 
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