ADFR therapy

(redirected from Activate, Depress, Free, Repeat)

ADFR Therapy

A catch-phrase for a way of managing post-menopausal bone loss in women for whom oestrogen therapy is contraindicated or unacceptable, by administering phosphorus, followed by calcitonin and calcium in 3 month cycles. The abbreviation translates as
A—Activate new bone cells.
D—Depress osteoclasts during the bone absorption period.
F—Free, relieve bone absorption and stimulate osteoblasts.
R—Repeat the cycle to increase bone density and quality.

ADFR therapy

Activate, depress, free, repeat A therapeutic modality–phosphorus, followed by calcitonin and calcium, administered in 3 month cycles, used to attenuate post-menopausal bone loss in ♀ for whom estrogen therapy is contraindicated or unacceptable