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pure red cell aplasia
(redirected from Acquired pure red cell aplasia)

   Also found in: Wikipedia 0.02 sec.
aplasia
defective development or complete absence of an organ or tissue due to failure of development.

aplasia cutis
see epitheliogenesis imperfecta.
pure red cell aplasia
selective depression of erythropoiesis with anemia resulting.
segmental aplasia
aplasia of a segment of an organ, e.g. uterus.

pure red cell aplasia
Hematology A type of anemia caused by selective depletion of erythroid cells
Pure red cell aplasia types
Acute Aplastic crisis A condition often preceded by viral gastroenteritis, pneumonitis, primary atypical pneumonia, mumps, viral hepatitis, pregnancy and drug toxicity Clinical Malaise, pallor and other symptoms of a chronic, compensated hemolyzing process Treatment The only effective modality is discontinuance of inculpated drug, if identified
Chronic Either 1.Congenital Diamond-Blackfan disease A condition due to a ↓ in erythrocyte stem cells with ↓ colony-forming units and burst-forming units and a poor response to erythropoietin Treatment Transfusions, corticosteroids or 2. Acquired 30-50% of chronic acquired PRCA is associated with thymoma, as well as rheumatoid arthritis, lupus erythematosus, chronic active hepatitis, hemolytic anemia and CLL  


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